High‐throughput sequencing for biology and medicine
WW Soon, M Hariharan, MP Snyder - Molecular systems biology, 2013 - embopress.org
Advances in genome sequencing have progressed at a rapid pace, with increased
throughput accompanied by plunging costs. But these advances go far beyond faster and …
throughput accompanied by plunging costs. But these advances go far beyond faster and …
[HTML][HTML] Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research
PK Grover, AG Cummins, TJ Price… - Annals of …, 2014 - Elsevier
Increasing evidence suggests that circulating tumour cells (CTCs) are responsible for
metastatic relapse and this has fuelled interest in their detection and quantification. Although …
metastatic relapse and this has fuelled interest in their detection and quantification. Although …
Early-stage lung cancer diagnosis by deep learning-based spectroscopic analysis of circulating exosomes
Lung cancer has a high mortality rate, but an early diagnosis can contribute to a favorable
prognosis. A liquid biopsy that captures and detects tumor-related biomarkers in body fluids …
prognosis. A liquid biopsy that captures and detects tumor-related biomarkers in body fluids …
[HTML][HTML] A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire
N Saucedo-Zeni, S Mewes… - International …, 2012 - spandidos-publications.com
The isolation of circulating tumor cells (CTCs) from the blood of patients afflicted with solid
malignant tumors becomes increasingly important as it may serve as a 'liquid biopsy'with the …
malignant tumors becomes increasingly important as it may serve as a 'liquid biopsy'with the …
Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation
Background The assessment of cell-free circulating DNA fragments, also known as a" liquid
biopsy" of the patient's plasma, is an important source for the discovery and subsequent non …
biopsy" of the patient's plasma, is an important source for the discovery and subsequent non …
Key molecular mechanisms in lung cancer invasion and metastasis: a comprehensive review
F Perlikos, KJ Harrington, KN Syrigos - Critical reviews in oncology …, 2013 - Elsevier
Lung cancer remains one of the most common and malignant cancers worldwide. It is most
often diagnosed at late stages, when it has already presented local invasion and distal …
often diagnosed at late stages, when it has already presented local invasion and distal …
Update on the types and usage of liquid biopsies in the clinical setting: a systematic review
B Arneth - BMC cancer, 2018 - Springer
Background This systematic review aimed to gather evidence from research on the current
state of liquid biopsy in medical practice, specifically focusing on mutation detection and …
state of liquid biopsy in medical practice, specifically focusing on mutation detection and …
Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds
TR Samatov, AG Tonevitsky, U Schumacher - Molecular cancer, 2013 - Springer
Epithelial-mesenchymal transition (EMT) is a key process in embryonic development and
metastases formation during malignant progression. This review focuses on transcriptional …
metastases formation during malignant progression. This review focuses on transcriptional …
Capturing cancer: emerging microfluidic technologies for the capture and characterization of circulating tumor cells
Circulating tumor cells (CTCs) escape from primary or metastatic lesions and enter into
circulation, carrying significant information of cancer progression and metastasis. Capture of …
circulation, carrying significant information of cancer progression and metastasis. Capture of …
[HTML][HTML] Current progress and mechanisms of bone metastasis in lung cancer: a narrative review
S Wu, Y Pan, Y Mao, Y Chen, Y He - Translational lung cancer …, 2021 - ncbi.nlm.nih.gov
Lung cancer is a kind of malignant tumor with rapid progression and poor prognosis. Distant
metastasis has been the main cause of mortality among lung cancer patients. Bone is one of …
metastasis has been the main cause of mortality among lung cancer patients. Bone is one of …