[HTML][HTML] A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis

LS Nolan, OB Parks, M Good - Nutrients, 2019 - mdpi.com
Breast milk contains immunomodulating components that are beneficial to newborns during
maturation of their immune system. Human breast milk composition is influenced by an …

[HTML][HTML] Phosphatidylserine receptors: enhancers of enveloped virus entry and infection

S Moller-Tank, W Maury - Virology, 2014 - Elsevier
A variety of both RNA and DNA viruses envelop their capsids in a lipid bilayer. One of the
more recently appreciated benefits this envelope is incorporation of phosphatidylserine …

[HTML][HTML] MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB …

Y Lu, L Liu, J Pan, B Luo, H Zeng, Y Shao… - Cell death & …, 2021 - nature.com
Milk fat globule-epidermal growth factor (EGF) factor 8 (MFG-E8), as a necessary bridging
molecule between apoptotic cells and phagocytic cells, has been widely studied in various …

[HTML][HTML] PET imaging of inflammation biomarkers

C Wu, F Li, G Niu, X Chen - Theranostics, 2013 - ncbi.nlm.nih.gov
Inflammation plays a significant role in many disease processes. Development in molecular
imaging in recent years provides new insight into the diagnosis and treatment evaluation of …

Osteopontin in immune-mediated diseases

SR Rittling, R Singh - Journal of dental research, 2015 - journals.sagepub.com
Since its initial identification as one of the genes most highly upregulated upon T-cell
activation, osteopontin (or Eta-1, as it was designated then) has been demonstrated to have …

Macrophage Smad3 protects the infarcted heart, stimulating phagocytosis and regulating inflammation

B Chen, S Huang, Y Su, YJ Wu, A Hanna… - Circulation …, 2019 - Am Heart Assoc
Rationale: TGF (transforming growth factor)-β is critically involved in myocardial injury,
repair, and fibrosis, activating both Smad (small mothers against decapentaplegic) …

[HTML][HTML] Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis

FN Soki, AJ Koh, JD Jones, YW Kim, J Dai… - Journal of Biological …, 2014 - ASBMB
Tumor cells secrete factors that modulate macrophage activation and polarization into M2
type tumor-associated macrophages, which promote tumor growth, progression, and …

milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation

M Aziz, A Jacob, A Matsuda, P Wang - Apoptosis, 2011 - Springer
Although the cloning and molecular characterization of MFG-E8 was first reported in the
early 90s, breakthrough on MFG-E8 research came into light when it was explored as an …

Effects of RGD-grafted phosphatidylserine-containing liposomes on the polarization of macrophages and bone tissue regeneration

L Wu, Y Kim, GM Seon, SH Choi, HC Park, G Son… - Biomaterials, 2021 - Elsevier
Phosphatidylserine-containing liposomes (PSLs) can mimic the anti-inflammatory effects of
apoptotic cells by binding to the phosphatidylserine receptors of macrophages. MGF-E8, a …

[HTML][HTML] MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

N Deroide, X Li, D Lerouet, E Van Vré… - The Journal of …, 2013 - Am Soc Clin Investig
Milk fat globule-EGF 8 (MFGE8) plays important, nonredundant roles in several biological
processes, including apoptotic cell clearance, angiogenesis, and adaptive immunity …