Lighting up tumors with receptor-specific optical molecular probes
S Achilefu - Technology in cancer research & treatment, 2004 - journals.sagepub.com
Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …
Imaging angiogenesis: applications and potential for drug development
JC Miller, HH Pien, D Sahani… - Journal of the …, 2005 - academic.oup.com
Recognition of the importance of angiogenesis to tumor growth and metastasis has led to
efforts to develop new drugs that are targeted to angiogenic vasculature. Clinical trials of …
efforts to develop new drugs that are targeted to angiogenic vasculature. Clinical trials of …
Imaging of integrin αvβ3 expression
AJ Beer, M Schwaiger - Cancer and metastasis reviews, 2008 - Springer
The integrin αvβ3 plays an important role in angiogenesis and tumor metastasis. It is
expressed on activated endothelial cells as well as some tumor cells. Therefore it is a …
expressed on activated endothelial cells as well as some tumor cells. Therefore it is a …
All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast
EMC Hillman, A Moore - Nature photonics, 2007 - nature.com
Optical molecular imaging in small animals harnesses the power of highly specific and
biocompatible contrast agents for drug development and disease research,,,,,,. However, the …
biocompatible contrast agents for drug development and disease research,,,,,,. However, the …
Confocal mosaicing microscopy in Mohs skin excisions: feasibility of rapid surgical pathology
DS Gareau, Y Li, B Huang, Z Eastman… - … of biomedical optics, 2008 - spiedigitallibrary.org
Mosaicing of confocal images enables observation of nuclear morphology in large areas of
tissue. An application of interest is rapid detection of basal cell carcinomas (BCCs) in skin …
tissue. An application of interest is rapid detection of basal cell carcinomas (BCCs) in skin …
Time-dependent whole-body fluorescence tomography of probe bio-distributions in mice
SV Patwardhan, SR Bloch, S Achilefu, JP Culver - Optics Express, 2005 - opg.optica.org
We present a fast scanning fluorescence optical tomography system for imaging the kinetics
of probe distributions through out the whole body of small animals. Configured in a plane …
of probe distributions through out the whole body of small animals. Configured in a plane …
Diffuse optical tomography with a priori anatomical information
Diffuse optical tomography (DOT) poses a typical ill-posed inverse problem with a limited
number of measurements and inherently low spatial resolution. In this paper, we propose a …
number of measurements and inherently low spatial resolution. In this paper, we propose a …
In vivo optical imaging and dynamic contrast methods for biomedical research
EMC Hillman, CB Amoozegar… - … of the Royal …, 2011 - royalsocietypublishing.org
This paper provides an overview of optical imaging methods commonly applied to basic
research applications. Optical imaging is well suited for non-clinical use, since it can exploit …
research applications. Optical imaging is well suited for non-clinical use, since it can exploit …
[HTML][HTML] Combined effects of laser-ICG photothermotherapy and doxorubicin chemotherapy on ovarian cancer cells
Y Tang, AJ McGoron - Journal of Photochemistry and Photobiology B …, 2009 - Elsevier
Doxorubicin (DOX) is an anthracycline antibiotic widely used in cancer chemotherapy. Its
use is limited by cardiac toxicity and drug resistance. Hyperthermia can aid the functionality …
use is limited by cardiac toxicity and drug resistance. Hyperthermia can aid the functionality …
Spatial variations in optical and physiological properties of healthy breast tissue
N Shah, AE Cerussi, D Jakubowski… - … of biomedical optics, 2004 - spiedigitallibrary.org
Near-infrared (NIR) diffuse optical spectroscopy (DOS) and diffuse optical imaging (DOI)
show promise as noninvasive clinical techniques for breast cancer screening and diagnosis …
show promise as noninvasive clinical techniques for breast cancer screening and diagnosis …