Alzheimer's disease (AD) is a complex, progressive primary neurodegenerative disease.
Since pivotal genetic studies in 1993, the ε4 allele of the apolipoprotein E gene (APOE ε4) …

Purpose To evaluate the potential of retinal optical coherence tomography (OCT)
measurements and polygenic risk scores (PRS) to identify people at risk of cognitive …

Abstract Background Both Alzheimer's disease (AD) genetic risk factors and indices of
cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether …

Genetic factors play a major role in the development of Alzheimer's disease and related
dementias (ADRD). With increased access to genetic data, observable genetic factors could …

INTRODUCTION We sought to characterize the timing of changes in cognitive trajectories
related to genetic risk using the apolipoprotein E (APOE) score, a continuous measure of …

Abstract Background Predicting future Alzheimer's disease (AD)-related cognitive decline
among individuals with subjective cognitive decline (SCD) or mild cognitive impairment …

Disentangling genetic risks for development and progression of Alzheimer’s disease | Brain |
Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals Books …

Abstract Apolipoprotein E (APOE) ε4, the strongest genetic risk factor for late onset
Alzheimer's disease (LOAD), has been associated with cognitive decline independent from …

INTRODUCTION The development and progression of Alzheimer's disease (AD) is a
complex process, during which genetic influences on phenotypes may also change …

Objective Demographic and disease factors are associated with cognitive deficits and
postoperative cognitive declines in adults with pharmacoresistant temporal lobe epilepsy …