A pharmacological update of ellagic acid
JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …
present either in free form or as part of more complex molecules (ellagitannins), which can …
Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy
W Liu, X Cui, Y Zhong, R Ma, B Liu, Y Xia - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …
[HTML][HTML] The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art
G Lu, X Wang, M Cheng, S Wang, K Ma - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ellagic acid (EA) is a kind of polyphenol compound extracted from a variety of herbs, such as
paeoniae paeoniae, raspberry, Chebule, walnut kernel, myrrh, loquat leaf, pomegranate …
paeoniae paeoniae, raspberry, Chebule, walnut kernel, myrrh, loquat leaf, pomegranate …
MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming
Z Zhang, TE Li, M Chen, D Xu, Y Zhu, BY Hu… - British journal of …, 2020 - nature.com
Background Mitochondrial dynamics plays an important role in tumour progression.
However, how these dynamics integrate tumour metabolism in hepatocellular carcinoma …
However, how these dynamics integrate tumour metabolism in hepatocellular carcinoma …
Phenolic compounds cannabidiol, curcumin and quercetin cause mitochondrial dysfunction and suppress acute lymphoblastic leukemia cells
Anticancer activity of different phenols is documented, but underlying mechanisms remain
elusive. Recently, we have shown that cannabidiol kills the cells of acute lymphoblastic …
elusive. Recently, we have shown that cannabidiol kills the cells of acute lymphoblastic …
Ellagic acid: a logical lead for drug development?
Background: Naturally occurring polyphenols are the subject of increasing attention due to
their potent antioxidant activity and their marked effects on the prevention of various …
their potent antioxidant activity and their marked effects on the prevention of various …
Mitochondrial transplantation as a potential and novel master key for treatment of various incurable diseases
AM Roushandeh, Y Kuwahara, MH Roudkenar - Cytotechnology, 2019 - Springer
Mitochondria are attractive cellular organelles which are so interesting in both basic and
clinical research, especially after it was found that they were arisen as a bacterial intruder in …
clinical research, especially after it was found that they were arisen as a bacterial intruder in …
Selective cytotoxicity of luteolin and kaempferol on cancerous hepatocytes obtained from rat model of hepatocellular carcinoma: involvement of ROS-mediated …
To evaluate the cytotoxicity effects of luteolin (LUT) and kaempferol (KAE) via reactive
oxygen species (ROS) mediated mitochondrial targeting on hepatocytes obtained from the …
oxygen species (ROS) mediated mitochondrial targeting on hepatocytes obtained from the …
[HTML][HTML] SA inhibits complex III activity to generate reactive oxygen species and thereby induces GA overproduction in Ganoderma lucidum
R Liu, P Cao, A Ren, S Wang, T Yang, T Zhu, L Shi… - Redox Biology, 2018 - Elsevier
Ganoderma lucidum has high commercial value because it produces many active
compounds, such as ganoderic acids (GAs). Salicylic acid (SA) was previously reported to …
compounds, such as ganoderic acids (GAs). Salicylic acid (SA) was previously reported to …