From the updated landscape of the emerging biologics for IBDs treatment to the new delivery systems

J Yang, D Li, M Zhang, G Lin, S Hu, H Xu - Journal of Controlled Release, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) treatments have shifted from small-molecular
therapeutics to the oncoming biologics. The first-line biologics against the moderate-to …

[HTML][HTML] Thermoresponsive nanogels based on different polymeric moieties for biomedical applications

S Ghaeini-Hesaroeiye, H Razmi Bagtash, S Boddohi… - Gels, 2020 - mdpi.com
Nanogels, or nanostructured hydrogels, are one of the most interesting materials in
biomedical engineering. Nanogels are widely used in medical applications, such as in …

Novel Application of NIR-I-absorbing quinoidal conjugated polymer as a photothermal therapeutic agent

Y Choi, K Min, N Han, G Tae… - ACS Applied Materials & …, 2023 - ACS Publications
Conjugated polymer nanoparticles (CP NPs) that could absorb the first near-infrared (NIR-I)
window have emerged as highly desirable therapeutic nanomaterials. Here, a quinoidal …

Design and evaluation of galactosylated chitosan/graphene oxide nanoparticles as a drug delivery system

C Wang, Z Zhang, B Chen, L Gu, Y Li, S Yu - Journal of colloid and …, 2018 - Elsevier
We investigated a novel drug delivery system comprising nanoparticles based on
galactosylated chitosan/graphene oxide/doxorubicin (GC–GO–DOX) for the therapeutic …

A supramolecular host-guest interaction-mediated injectable hydrogel system with enhanced stability and sustained protein release

SY Lee, SI Jeon, SB Sim, Y Byun, CH Ahn - Acta Biomaterialia, 2021 - Elsevier
Injectable hydrogels have been studied as drug delivery systems because of their minimal
invasiveness and sustained drug release properties. Pluronic F127, consisting of poly …

Thermo-sensitive hydrogel with mussel-inspired adhesion enhanced the non-fibrotic repair effect of EGF on colonic mucosa barrier of TNBS-induced ulcerative colitis …

L Wang, J Xu, P Xue, J Liu, L Luo, D Zhuge… - Chemical Engineering …, 2021 - Elsevier
Thermo-sensitive hydrogel is preferable to liquid enema for topical treatments of ulcerative
colitis (UC). Poly (ethylene oxide)-poly (propylene oxide)-poly-(ethylene oxide) copolymer …

Bioinspired smart actuator based on graphene oxide-polymer hybrid hydrogels

T Wang, J Huang, Y Yang, E Zhang… - ACS applied materials …, 2015 - ACS Publications
Rapid response and strong mechanical properties are desired for smart materials used in
soft actuators. A bioinspired hybrid hydrogel actuator was designed and prepared by series …

Irinotecan-loaded double-reversible thermogel with improved antitumor efficacy without initial burst effect and toxicity for intramuscular administration

F ud Din, DW Kim, JY Choi, RK Thapa, O Mustapha… - Acta biomaterialia, 2017 - Elsevier
Intramuscularly administered, anti-tumour drugs induce severe side effects due to their direct
contact with body tissues and initial burst effect. In this study, to solve this problem, a novel …

Synthesis of a novel thermo/pH sensitive nanogel based on salep modified graphene oxide for drug release

GR Bardajee, Z Hooshyar, M Farsi, A Mobini… - Materials Science and …, 2017 - Elsevier
Nanogels (NGs) are three-dimensional water soluble cross-linked hydrogel materials in the
nanoscale size range with a high loading capacity for guest molecules and act as drug …

Injectable poloxamer/graphene oxide hydrogels with well‐controlled mechanical and rheological properties

E Rohani Rad, H Vahabi, K Formela… - Polymers for …, 2019 - Wiley Online Library
Although significant progress has been made in the design and application of injectable
hydrogels for biomedical applications, concurrent control of rheological and mechanical …