[HTML][HTML] Cadmium and lead exposure, nephrotoxicity, and mortality

S Satarug, G C. Gobe, D A. Vesey, KR Phelps - Toxics, 2020 - mdpi.com
The present review aims to provide an update on health risks associated with the low-to-
moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations …

The complexity of kidney disease and diagnosing it–cystatin C, selective glomerular hypofiltration syndromes and proteome regulation

L Malmgren, C Öberg, E den Bakker… - Journal of internal …, 2023 - Wiley Online Library
Estimation of kidney function is often part of daily clinical practice, mostly done by using the
endogenous glomerular filtration rate (GFR)‐markers creatinine or cystatin C. A …

[HTML][HTML] The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

MG Shlipak, SL Tummalapalli, LE Boulware… - Kidney international, 2021 - Elsevier
Chronic kidney disease (CKD) causes substantial global morbidity and increases
cardiovascular and all-cause mortality. Unlike other chronic diseases with established …

[HTML][HTML] Discovery and prioritization of variants and genes for kidney function in> 1.2 million individuals

KJ Stanzick, Y Li, P Schlosser, M Gorski… - Nature …, 2021 - nature.com
Genes underneath signals from genome-wide association studies (GWAS) for kidney
function are promising targets for functional studies, but prioritizing variants and genes is …

Inflammation and oxidative stress in chronic kidney disease and dialysis patients

T Ebert, O Neytchev, A Witasp… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

[HTML][HTML] Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease

AAZ Dawoud, RD Gilbert, WJ Tapper, NCP Cross - Leukemia, 2022 - nature.com
We sought to determine the relationship between age-related clonal hematopoiesis (CH)
and chronic kidney disease (CKD). CH, defined as mosaic chromosome abnormalities …

Comparison of cystatin C and creatinine in the assessment of measured kidney function during critical illness

RW Haines, AJ Fowler, K Liang… - Clinical Journal of the …, 2023 - journals.lww.com
Background Incomplete recovery of kidney function is an important adverse outcome in
survivors of critical illness. However, unlike eGFR creatinine, eGFR cystatin C is not …

Novel prediction equations for absolute risk assessment of total cardiovascular disease incorporating cardiovascular-kidney-metabolic health: a scientific statement …

SS Khan, J Coresh, MJ Pencina, CE Ndumele… - Circulation, 2023 - Am Heart Assoc
Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …

A Mendelian randomization study found causal linkage between telomere attrition and chronic kidney disease

S Park, S Lee, Y Kim, S Cho, K Kim, YC Kim, SS Han… - Kidney International, 2021 - Elsevier
Chronic kidney disease (CKD) is highly prevalent in the elderly population. However, it is
rarely investigated whether kidney function is causally linked to biological aging itself. In this …

Application of SERS-based nanobiosensors to metabolite biomarkers of CKD

D Kukkar, M Chhillar, KH Kim - Biosensors and Bioelectronics, 2023 - Elsevier
A clinical diagnosis of chronic kidney disease (CKD) is commonly achieved by estimating
the serum levels of urea and creatinine (CR). Given the limitations of the conventional …