Novel prediction equations for absolute risk assessment of total cardiovascular disease incorporating cardiovascular-kidney-metabolic health: a scientific statement …

SS Khan, J Coresh, MJ Pencina, CE Ndumele… - Circulation, 2023 - Am Heart Assoc
Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …

[HTML][HTML] Cadmium and lead exposure, nephrotoxicity, and mortality

S Satarug, G C. Gobe, D A. Vesey, KR Phelps - Toxics, 2020 - mdpi.com
The present review aims to provide an update on health risks associated with the low-to-
moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations …

Development and validation of the American Heart Association's PREVENT equations

SS Khan, K Matsushita, Y Sang, SH Ballew… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Multivariable equations are recommended by primary prevention
guidelines to assess absolute risk of cardiovascular disease (CVD). However, current …

[HTML][HTML] The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

MG Shlipak, SL Tummalapalli, LE Boulware… - Kidney international, 2021 - Elsevier
Chronic kidney disease (CKD) causes substantial global morbidity and increases
cardiovascular and all-cause mortality. Unlike other chronic diseases with established …

[HTML][HTML] Discovery and prioritization of variants and genes for kidney function in> 1.2 million individuals

KJ Stanzick, Y Li, P Schlosser, M Gorski… - Nature …, 2021 - nature.com
Genes underneath signals from genome-wide association studies (GWAS) for kidney
function are promising targets for functional studies, but prioritizing variants and genes is …

Inflammation and oxidative stress in chronic kidney disease and dialysis patients

T Ebert, O Neytchev, A Witasp… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

The complexity of kidney disease and diagnosing it–cystatin C, selective glomerular hypofiltration syndromes and proteome regulation

L Malmgren, C Öberg, E den Bakker… - Journal of internal …, 2023 - Wiley Online Library
Estimation of kidney function is often part of daily clinical practice, mostly done by using the
endogenous glomerular filtration rate (GFR)‐markers creatinine or cystatin C. A …

[HTML][HTML] Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease

AAZ Dawoud, RD Gilbert, WJ Tapper, NCP Cross - Leukemia, 2022 - nature.com
We sought to determine the relationship between age-related clonal hematopoiesis (CH)
and chronic kidney disease (CKD). CH, defined as mosaic chromosome abnormalities …

Removing race from the CKD-EPI equation and its impact on prognosis in a predominantly White European population

EL Fu, J Coresh, ME Grams, CM Clase… - Nephrology Dialysis …, 2023 - academic.oup.com
ABSTRACT Background While American nephrology societies recommend using the 2021
Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular …

[HTML][HTML] Advantages, limitations, and clinical considerations in using cystatin C to estimate GFR

DC Chen, OA Potok, D Rifkin, MM Estrella - Kidney360, 2022 - journals.lww.com
Cystatin C has been shown to be a reliable and accurate marker of kidney function across
diverse populations. The 2012 Kidney Disease Improving Global Outcomes (KDIGO) …