Neoantigen, as an important member of tumor-specific antigens, has attracted a great deal
of attention as a target for immunotherapy. Neoantigens are potential targets for …

Purpose: DNA mismatch repair (MMR) deficiency is a hallmark of Lynch syndrome, the most
common inherited cancer syndrome. MMR-deficient cancer cells accumulate numerous …

Microsatellite instability‑high/deficient mismatch repair colorectal cancer (MSI‑H/dMMR
CRC) is a molecular subtype characterized by high‑frequency mutations within DNA …

Like many other types of cancer, colorectal cancer (CRC) develops through multiple
pathways of carcinogenesis. This is also true for colorectal carcinogenesis in Lynch …

Since millions of cancer-related deaths and diagnoses exist yearly, malignant tumors are a
primary worldwide health concern. A promising method for treating cancer is tumor …

Regular colonoscopy even with short intervals does not prevent all colorectal cancers (CRC)
in Lynch syndrome (LS). In the present study, we asked whether cancers detected under …

Введение. Периоперационная химиотерапия по схеме FLOT улучшает прогноз у
пациентов с местно-распространенным раком желудка (РЖ). Однако более чем в 50 …