Cytokine storm in COVID-19: immunopathogenesis and therapy
C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
[HTML][HTML] Repurposing methylene blue in the management of COVID-19: Mechanistic aspects and clinical investigations
The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is the most recent
coronaviruses, which has infected humans, and caused the disease COVID-19. The World …
coronaviruses, which has infected humans, and caused the disease COVID-19. The World …
[HTML][HTML] Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern
Endemic human coronaviruses (hCoVs) 229E and OC43 cause respiratory disease with
recurrent infections, while severe acute respiratory syndrome (SARS)-CoV-2 spreads across …
recurrent infections, while severe acute respiratory syndrome (SARS)-CoV-2 spreads across …
[HTML][HTML] Mesoporous onion-like carbon nanostructures from natural oil for high-performance supercapacitor and electrochemical sensing applications: Insights into the …
Although onion-like carbon nanostructures (OLCs) are attractive materials for energy
storage, their commercialization is hampered by the absence of a simple, cost-effective …
storage, their commercialization is hampered by the absence of a simple, cost-effective …
Methylene blue is a nonspecific protein–protein interaction inhibitor with potential for repurposing as an antiviral for COVID-19
ST Chuang, H Papp, A Kuczmog, R Eells… - Pharmaceuticals, 2022 - mdpi.com
We have previously identified methylene blue, a tricyclic phenothiazine dye approved for
clinical use for the treatment of methemoglobinemia and for other medical applications as a …
clinical use for the treatment of methemoglobinemia and for other medical applications as a …
Methylene blue: a controversial diagnostic acid and medication?
M Bužga, E Machytka, E Dvořáčková… - Toxicology …, 2022 - academic.oup.com
A narrative review of the literature was conducted to determine if the administration of
methylene blue (MB) in humans has potential risks. Studies were identified from MEDLINE …
methylene blue (MB) in humans has potential risks. Studies were identified from MEDLINE …
[HTML][HTML] Exploring autophagy in treating SARS-CoV-2 spike protein-related pathology
MTJ Halma, PE Marik, YM Saleeby - Endocrine and Metabolic Science, 2024 - Elsevier
Fasting, a practice with historical roots in various cultures, has recently garnered significant
interest in the field of medicine. In this article, we delve into the mechanisms underlying …
interest in the field of medicine. In this article, we delve into the mechanisms underlying …
Toxicity of the spike protein of COVID-19 is a redox shift phenomenon: A novel therapeutic approach
L Schwartz, M Aparicio-Alonso, M Henry… - Free Radical Biology …, 2023 - Elsevier
We previously demonstrated that most diseases display a form of anabolism due to
mitochondrial impairment: in cancer, a daughter cell is formed; in Alzheimer's disease …
mitochondrial impairment: in cancer, a daughter cell is formed; in Alzheimer's disease …
In vitro evaluation of the antiviral activity of methylene blue alone or in combination against SARS-CoV-2
M Gendrot, P Jardot, O Delandre, M Boxberger… - Journal of Clinical …, 2021 - mdpi.com
A new severe acute respiratory syndrome coronavirus (SARS-CoV-2) causing coronavirus
diseases 2019 (COVID-19), which emerged in Wuhan, China in December 2019, has …
diseases 2019 (COVID-19), which emerged in Wuhan, China in December 2019, has …
Methylene blue for COVID-19 ARDS: insights from a randomized Clinical Trial
ZS Sanei, F Shahrahmani, B Khaleghi Manesh… - Naunyn-Schmiedeberg's …, 2024 - Springer
Background Around the world, the COVID-19 pandemic has presented many difficulties, and
acute respiratory distress syndrome (ARDS) has become a major worry. The antiviral and …
acute respiratory distress syndrome (ARDS) has become a major worry. The antiviral and …