The front and rear of collective cell migration

R Mayor, S Etienne-Manneville - Nature reviews Molecular cell biology, 2016 - nature.com
Collective cell migration has a key role during morphogenesis and during wound healing
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …

Collective behaviors of active matter learning from natural taxes across scales

F Ji, Y Wu, M Pumera, L Zhang - Advanced Materials, 2023 - Wiley Online Library
Taxis orientation is common in microorganisms, and it provides feasible strategies to
operate active colloids as small‐scale robots. Collective taxes involve numerous units that …

Collective cell migration: guidance principles and hierarchies

A Haeger, K Wolf, MM Zegers, P Friedl - Trends in cell biology, 2015 - cell.com
Collective cell migration results from the establishment and maintenance of collective
polarization, mechanocoupling, and cytoskeletal kinetics. The guidance of collective cell …

[HTML][HTML] Vitamin D: production, metabolism and mechanisms of action

DD Bikle - 2015 - europepmc.org
Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …

Mechanical force-driven adherens junction remodeling and epithelial dynamics

D Pinheiro, Y Bellaiche - Developmental cell, 2018 - cell.com
During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs)
ensure intercellular adhesion and tissue integrity while allowing for cell and tissue …

Collective cell migration: a physics perspective

V Hakim, P Silberzan - Reports on Progress in Physics, 2017 - iopscience.iop.org
Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

Physical models of collective cell motility: from cell to tissue

BA Camley, WJ Rappel - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Enhanced adipose-derived stem cells with IGF-1-modified mRNA promote wound healing following corneal injury

F Yu, D Gong, D Yan, H Wang, N Witman, Y Lu, W Fu… - Molecular Therapy, 2023 - cell.com
The cornea serves as an important barrier structure to the eyeball and is vulnerable to
injuries, which may lead to scarring and blindness if not treated promptly. To explore an …

Metformin Sensitizes EGFR-TKI–Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal

L Li, R Han, H Xiao, C Lin, Y Wang, H Liu, K Li… - Clinical cancer …, 2014 - AACR
Purpose: The EGF receptor tyrosine kinase inhibitors (EGFR-TKI) have become a standard
therapy in patients with EGFR-activating mutations. Unfortunately, acquired resistance …

Bioelectric signaling: role of bioelectricity in directional cell migration in wound healing

M Zhao, M Rolandi, RR Isseroff - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
In wound healing, individual cells' behaviors coordinate movement toward the wound center
to restore small or large barrier defects. The migration of epithelial cells as a continuous …