Alzheimer's disease (AD) is an age-related devastating neurodegenerative disorder, which
severely impacts on the global economic development and healthcare system. Though AD …

Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia.
It can linger for many years, but ultimately is fatal, the 6th leading cause of death …

Abstract [18 F]-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) is a widely
used diagnostic tool that can detect and quantify pathophysiology, as assessed through …

Loss of cognitive function is one the most devastating manifestations of ageing and vascular
disease. Cognitive decline is rapidly becoming an important cause of disability worldwide …

Background Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and
non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease …

In recent years, numerous in vivo molecular imaging probes have been developed. As a
consequence, much has been published on the design and synthesis of molecular imaging …

In recent years, multifunctional nanoparticles (NPs) consisting of either metal (eg Au), or
magnetic NP (eg iron oxide) with other fluorescent components such as quantum dots (QDs) …

The oligomer hypothesis for Alzheimer's disease (AD) was introduced in 1998. It was based
on evidence that oligomers could exist free of amyloid fibrils, that fibril-free oligomer …

The blood-brain barrier (BBB) is a specialized vascular system that impedes entry of all
large and the vast majority of small molecules including the most potent central nervous …

Early diagnosis of diseases (before they become advanced and incurable) is essential to
reduce morbidity and mortality rates. With the advent of novel technologies in clinical …