A lack of inhibition, particularly that mediated by gamma-amino butyric acid (GABA), the
main inhibitory transmitter of the central nervous system (CNS), is responsible for many pain …

Alzheimer's disease (AD) is characterized by an early synaptic loss, which strongly
correlates with the severity of dementia. The pathogenesis and causes of characteristic AD …

J. Neurochem.(2011) 119, 460–473. Abstract We studied the localization, activation and
function of protease‐activated receptor 1 (PAR‐1) at the CNS synapse utilizing rat brain …

We report that cholesterol depletion with methyl-β-cyclodextrin (MβCD) acutely applied to rat
brain synaptosomes is accompanied by an immediate increase in transporter-mediated …

A decrease in the osmolarity of incubation medium is accompanied by calcium influx in
neuronal presynaptic endings. We studied the influence of Ca2+ on exocytosis induced by …

The effects of extracellular monocarboxylates pyruvate and lactate on membrane potentials,
acidification and neurotransmitter filling of synaptic vesicles were investigated in …

Background Nitric oxide (NO) is an important presynaptic modulator of synaptic
transmission. Here, we aimed to correlate the release of the major inhibitory …

We investigated the production of reactive oxygen species (ROS) as a response to
presynaptic glutamate receptor activation, and the role of ROS in neurotransmitter (GABA) …

Neurotransmitter release is dependent on both calcium and sodium influx. Hypotonic
swelling and hypertonic shrinking of neurons evokes calcium-independent exocytosis of …

Phenylarsine oxide (PAO) has a number of targets in the neurons, one of them is exocytotic
process. In this study, we have focused on the mechanisms of phenylarsine oxide action on …