Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

The cytosolic selenoprotein thioredoxin reductase 1 (TrxR1, TXNRD1), and to some extent
mitochondrial TrxR2 (TXNRD2), can be inhibited by a wide range of electrophilic …

Significance: Thioredoxin (Trx) is a powerful antioxidant that reduces protein disulfides to
maintain redox stability in cells and is involved in regulating multiple redox-dependent …

Abstract AuI‐carbene and PtIV− AuI‐carbene prodrugs display low to sub‐μM activity
against several cancer cell lines and overcome cisplatin (cisPt) resistance. Linking a cisPt …

Based on their strong σ-donor properties N-heterocyclic carbene (NHC) ligands can form
stable complexes with many transition metals. Numerous applications of metal NHC …

Breast cancer is one of the top causes of death, particularly among women, and it affects
many women. Cancer can also be caused by various factors, including acquiring genetic …

A novel alkynyl phosphane gold (I) complex (trimethylphosphane)(3‐(1, 3‐dimethylxanthine‐
7‐yl) prop‐1‐yn‐1‐yl) gold (I) 1 displayed mutiple biological activites including selective …

Oxaliplatin (Oxa)-associated adverse side effects have considerably limited the clinical use
of the drug in colon cancer therapy. Mutant p53 has diverse mutational profiles in colon …

Glioblastoma multiforme (GBM) is the deadliest primary central nervous system tumor.
miRNAs (miRs), a class of non-coding RNAs, are considered pivotal post-transcriptional …