5, 8-Quinolinedione scaffold as a promising moiety of bioactive agents

M Kadela-Tomanek, E Bębenek, E Chrobak… - Molecules, 2019 - mdpi.com
Natural 5, 8-quinolinedione antibiotics exhibit a broad spectrum of activities including
anticancer, antibacterial, antifungal, and antimalarial activities. The structure–activity …

The Synthesis and Chemistry of Quinolinediones and their Carbocyclic Analogs

SA Egu, EA Onoabedje, UC Okoro… - Mini-Reviews in …, 2022 - ingentaconnect.com
Quinoline-5, 8-dione and naphthoquinone nuclei are very important substructures in
industrial chemicals and pharmaceuticals. These compounds exhibit a wide variety of …

Double alkynylation of quinoline-5, 8-diones and their in-silico and antimicrobial studies

MA Ezeokonkwo, JA Ezugwu, SN Okafor… - Journal of Applied …, 2018 - ajol.info
A double alkynylation of quinoline-5, 8-dione to furnished bis-alkynylquinoline-5, 8-dione in
good yields and their in silico and antimicrobial studies is described. This was achieved by …