Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
INTRODUCTION Retinal is a light-sensitive protein ligand that is used by all domains of life
to process the information and energy content of light. Retinal-binding proteins are integral …
to process the information and energy content of light. Retinal-binding proteins are integral …
Structural insights into functional properties of the oxidized form of cytochrome c oxidase
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …
[PDF][PDF] Recent developments in CrystFEL
CrystFEL is a suite of programs for processing data fromserial crystallography'experiments,
which are usually performed using X-ray free-electron lasers (FELs) but also increasingly …
which are usually performed using X-ray free-electron lasers (FELs) but also increasingly …
Current status of single particle imaging with X-ray lasers
The advent of ultrafast X-ray free-electron lasers (XFELs) opens the tantalizing possibility of
the atomic-resolution imaging of reproducible objects such as viruses, nanoparticles, single …
the atomic-resolution imaging of reproducible objects such as viruses, nanoparticles, single …
Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition
Light-driven oxidation of water to molecular oxygen is catalyzed by the oxygen-evolving
complex (OEC) in Photosystem II (PS II). This multi-electron, multi-proton catalysis requires …
complex (OEC) in Photosystem II (PS II). This multi-electron, multi-proton catalysis requires …
Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses
X-ray free-electron lasers (XFELs) enable crystallographic structure determination beyond
the limitations imposed upon synchrotron measurements by radiation damage. The need for …
the limitations imposed upon synchrotron measurements by radiation damage. The need for …
[PDF][PDF] OnDA: online data analysis and feedback for serial X-ray imaging
This article describes a free and open-source data analysis utility designed for fast online
feedback during serial X-ray diffraction and scattering experiments: OnDA (online data …
feedback during serial X-ray diffraction and scattering experiments: OnDA (online data …
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing
The COVID-19 pandemic has resulted in 198 million reported infections and more than 4
million deaths as of July 2021 (covid19. who. int). Research to identify effective therapies for …
million deaths as of July 2021 (covid19. who. int). Research to identify effective therapies for …
Multi-frame, ultrafast, x-ray microscope for imaging shockwave dynamics
Inertial confinement fusion (ICF) holds increasing promise as a potential source of abundant,
clean energy, but has been impeded by defects such as micro-voids in the ablator layer of …
clean energy, but has been impeded by defects such as micro-voids in the ablator layer of …
Accurate prediction of X-ray pulse properties from a free-electron laser using machine learning
A Sanchez-Gonzalez, P Micaelli, C Olivier… - Nature …, 2017 - nature.com
Free-electron lasers providing ultra-short high-brightness pulses of X-ray radiation have
great potential for a wide impact on science, and are a critical element for unravelling the …
great potential for a wide impact on science, and are a critical element for unravelling the …