Listen to an interview with Tom Rando on the stem cells podcast Adult stem cells reside in
most mammalian tissues, but the extent to which they contribute to normal homeostasis and …

How do animals regenerate specialised tissues or their entire body after a traumatic injury,
how has this ability evolved and what are the genetic and cellular components underpinning …

Differentiated cells possess a remarkable genomic plasticity that can be manipulated to
reverse or change developmental commitments. Here, we show that the leprosy bacterium …

Regenerative potential is expressed to a maximum extent in echinoderms. It is a common
phenomenon in all the classes, extensively employed to reconstruct external appendages …

Cnidarians possess remarkable powers of regeneration, but the cellular and molecular
mechanisms underlying this capability are unclear. Studying the hydrozoan Hydractinia …

Which genes and gene signaling pathways mediate regenerative processes? In recent
years, multiple studies, using a variety of animal models, have aimed to answer this …

Visceral regeneration in sea cucumbers has been studied since early last century; however,
it is only within the last 15 years that real progress has been made in understanding the …

Background Among deuterostomes, the regenerative potential is maximally expressed in
echinoderms, animals that can quickly replace most injured organs. In particular, sea …

Coelomocytes are recognized as the main cellular component of the echinoderm immune
system. They are the first line of defense and their number and type can vary dramatically …

Neuronal secretion of peptide signaling molecules (neuropeptides) is an evolutionarily
ancient feature of nervous systems. Here we report the identification of 20 cDNAs encoding …