Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …

Background The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could
develop into a substantial health problem worldwide. Whether diet, physical activity or both …

OBJECTIVE Understanding the real-world impacts of lifestyle modification (LSM) for
diabetes prevention is imperative to inform resource allocation. The purpose of this study …

Objectives To assess diagnostic accuracy of screening tests for pre-diabetes and efficacy of
interventions (lifestyle or metformin) in preventing onset of type 2 diabetes in people with pre …

OBJECTIVE To summarize the evidence on effectiveness of translational diabetes
prevention programs, based on promoting lifestyle change to prevent type 2 diabetes in real …

Aims To assess the efficacy, safety, and cost-effectiveness of lifestyle intervention, compared
with treatment as usual in people with prediabetes as defined by the American Diabetes …

Background The evidence base for the prevention of type 2 diabetes mellitus (T2DM) has
progressed rapidly from efficacy trials to real-world translational studies and practical …

Diabetes is a costly disease affecting 387 million individuals globally and 28 million in the
United States. Its precursor, prediabetes, affects 316 and 86 million individuals globally and …

We conducted a systematic review and meta-analysis of twenty-eight US-based studies
applying the findings of the Diabetes Prevention Program, a clinical trial that tested the …

Background Type 2 diabetes is a significant public health concern. With the completion of
the Diabetes Prevention Program, there has been a proliferation of studies attempting to …