Repositioning TH cell polarization from single cytokines to complex help

S Tuzlak, AS Dejean, M Iannacone, FJ Quintana… - Nature …, 2021 - nature.com
When helper T (TH) cell polarization was initially described three decades ago, the TH cell
universe grew dramatically. New subsets were described based on their expression of few …

Innate lymphoid cells and cancer

N Jacquelot, C Seillet, E Vivier, GT Belz - Nature Immunology, 2022 - nature.com
The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

[HTML][HTML] Innate lymphoid cells: 10 years on

E Vivier, D Artis, M Colonna, A Diefenbach, JP Di Santo… - Cell, 2018 - cell.com
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019 - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

R Alon, M Sportiello, S Kozlovski, A Kumar… - Nature Reviews …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity

JA Moral, J Leung, LA Rojas, J Ruan, J Zhao, Z Sethna… - Nature, 2020 - nature.com
Group 2 innate lymphoid cells (ILC2s) regulate inflammation and immunity in mammalian
tissues,. Although ILC2s are found in cancers of these tissues, their roles in cancer immunity …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Plasticity of innate lymphoid cell subsets

SM Bal, K Golebski, H Spits - Nature Reviews Immunology, 2020 - nature.com
Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …

Heterogeneity of type 2 innate lymphoid cells

H Spits, J Mjösberg - Nature Reviews Immunology, 2022 - nature.com
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …