Vitamin D supplementation and the outcomes of critically ill adult patients: a systematic review and meta-analysis of randomized controlled trials

SH Lan, CC Lai, SP Chang, LC Lu, SH Hung… - Scientific Reports, 2020 - nature.com
This meta-analysis assessed the association between vitamin D supplementation and the
outcomes of critically ill adult patients. A literature search was conducted using the PubMed …

[HTML][HTML] Vitamin D supplementation in critically ill patients: a meta-analysis of randomized controlled trials

S Singh, S Sarkar, K Gupta, A Rout - Cureus, 2022 - ncbi.nlm.nih.gov
Randomized controlled trials (RCTs) have reported conflicting outcomes with the use of
vitamin D in critically ill patients. With reporting of newer RCTs, we conducted this updated …

A single large dose of vitamin D could be used as a means of coronavirus disease 2019 prevention and treatment

G Liu, T Hong, J Yang - Drug Design, Development and Therapy, 2020 - Taylor & Francis
There is no specific and effective medication for coronavirus disease 2019 (COVID-19), and
avaccine is not available in recent months. Here, we hypothesize that a single large dose of …

Vitamin D and acute and severe illness–a mechanistic and pharmacokinetic perspective

I Schoenmakers, WD Fraser, A Forbes - Nutrition Research Reviews, 2023 - cambridge.org
The coronavirus disease 2019 (COVID-19) pandemic has generated high interest in factors
modulating risk of infection, disease severity and recovery. Vitamin D has garnered interest …

Administration of vitamin D and its metabolites in critically ill adult patients: an updated systematic review with meta-analysis of randomized controlled trials

J Menger, ZY Lee, Q Notz, J Wallqvist, MS Hasan… - Critical Care, 2022 - Springer
Background The clinical significance of vitamin D administration in critically ill patients
remains inconclusive. The purpose of this systematic review with meta-analysis was to …

High dose vitamin D improves total serum antioxidant capacity and ICU outcome in critically ill patients-A randomized, double-blind clinical trial

M Sistanizad, M Kouchek, MM Miri, S Salarian… - European Journal of …, 2021 - Elsevier
Introduction Mechanical ventilation can increase the rate of free radicals in the systemic
circulation due to its effect on the inflammatory system. Previous research has suggested …

The effect of vitamin D supplementation on clinical outcomes for critically ill patients: a systemic review and meta-analysis of randomized clinical trials

H Shen, Y Mei, K Zhang, X Xu - Frontiers in Nutrition, 2021 - frontiersin.org
Purpose: Vitamin D deficiency is a common scenario in critically ill patients and has been
proven to be associated with poor outcomes. However, the effect of vitamin D …

A potential role of vitamin D on platelet leukocyte aggregation and pathological events in sepsis: an updated review

A Alharbi - Journal of Inflammation Research, 2021 - Taylor & Francis
Vitamin D deficiency and sepsis are both significant global health problems. Insufficient
vitamin D is considered to be a pathogenically relevant factor of sepsis-related deaths; …

The effects of vitamin D on all-cause mortality in different diseases: an evidence-map and umbrella review of 116 randomized controlled trials

M Cao, C He, M Gong, S Wu, J He - Frontiers in Nutrition, 2023 - frontiersin.org
Purpose To conduct a solid evidence by synthesizing meta-analyses and updated RCTs
about the effects of vitamin D on all-cause mortality in different health conditions. Methods …

Association between Vitamin D supplementation and mortality in critically ill patients: A systematic review and meta-analysis of randomized clinical trials

L Peng, L Li, P Wang, W Chong, Y Li, X Zha, H Deng… - PLoS …, 2020 - journals.plos.org
Background Observational studies suggest that low 25-hydroxyvitamin D status is common
and has been associated with higher mortality in critically ill patients. This study aim to …