Natural gums and modified natural gums as sustained-release carriers
TR Bhardwaj, M Kanwar, R Lal… - Drug development and …, 2000 - Taylor & Francis
Although natural gums and their derivatives are used widely in pharmaceutical dosage
forms, their use as biodegradable polymeric materials to deliver bioactive agents has been …
forms, their use as biodegradable polymeric materials to deliver bioactive agents has been …
Co-proccessed excipients with enhanced direct compression functionality for improved tableting performance
J Rojas, I Buckner, V Kumar - Drug development and industrial …, 2012 - Taylor & Francis
It is necessary to have excipients with excellent functional properties to compensate for the
poor mechanical properties and low aqueous solubility of the emerging active ingredients …
poor mechanical properties and low aqueous solubility of the emerging active ingredients …
Novel modified starch–xanthan gum hydrogels for controlled drug delivery: Synthesis and characterization
This work was intended to develop a new cross-linked gelatinized starch–xanthan gum
hydrogel system, to characterize the properties of the new material, and to explore its …
hydrogel system, to characterize the properties of the new material, and to explore its …
Swelling and drug release behaviour of xanthan gum matrix tablets
MM Talukdar, R Kinget - International Journal of Pharmaceutics, 1995 - Elsevier
The swelling and drug release behaviour of xanthan gum matrix tablets were studied using
three drugs having different properties, ie, caffeine as a soluble neutral drug, indomethacin …
three drugs having different properties, ie, caffeine as a soluble neutral drug, indomethacin …
Delivery of drugs to the lower GI tract
DR Friend, D Wong - US Patent 5,811,388, 1998 - Google Patents
Pharmaceutical compositions for orally delivering a therapeutically effective amount of a
drug to the colon without significant release of the drug in the upper GI tract after oral …
drug to the colon without significant release of the drug in the upper GI tract after oral …
Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
EI Lerner, V Rosenberger, M Flashner - US Patent 6,197,331, 2001 - Google Patents
4,059,686 11/1977 Tanaka et al..... 424/19 position for the oral cavity or “pharmaceutical oral
patch'4,386,106 5/1983 Merritt et al..... 426/5 that adheres to hard dental Surfaces, Such as …
patch'4,386,106 5/1983 Merritt et al..... 426/5 that adheres to hard dental Surfaces, Such as …
Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum
The objective of this investigation was to improve the stability of CLA and to allow for its
controlled release by encapsulating it with combinations of octenyl-succinic anhydride …
controlled release by encapsulating it with combinations of octenyl-succinic anhydride …
Evaluation of acrylamide-grafted-xanthan gum copolymer matrix tablets for oral controlled delivery of antihypertensive drugs
The present study was conducted to investigate the utilization of xanthan-grafted copolymer
of acrylamide (AAm) as a controlled release (CR) matrix for antihypertensive drugs such as …
of acrylamide (AAm) as a controlled release (CR) matrix for antihypertensive drugs such as …
Controlled release insufflation carrier for medicaments
A Baichwal, JN Staniforth - US Patent 5,612,053, 1997 - Google Patents
The advantages of controlled release products are well known in the pharmaceutical field
and include the ability to maintain a desired blood level of a medicament over a …
and include the ability to maintain a desired blood level of a medicament over a …
Guar-based monolithic matrix systems: effect of ionizable and non-ionizable substances and excipients on gel dynamics and release kinetics
T Dürig, R Fassihi - Journal of controlled release, 2002 - Elsevier
The effect of ionic and non-ionic excipients and additives as modulators of swelling and
erosion kinetics and verapamil HCl release from guar-based matrix tablets was investigated …
erosion kinetics and verapamil HCl release from guar-based matrix tablets was investigated …