Natural gums and modified natural gums as sustained-release carriers

TR Bhardwaj, M Kanwar, R Lal… - Drug development and …, 2000 - Taylor & Francis
Although natural gums and their derivatives are used widely in pharmaceutical dosage
forms, their use as biodegradable polymeric materials to deliver bioactive agents has been …

Co-proccessed excipients with enhanced direct compression functionality for improved tableting performance

J Rojas, I Buckner, V Kumar - Drug development and industrial …, 2012 - Taylor & Francis
It is necessary to have excipients with excellent functional properties to compensate for the
poor mechanical properties and low aqueous solubility of the emerging active ingredients …

Novel modified starch–xanthan gum hydrogels for controlled drug delivery: Synthesis and characterization

A Shalviri, Q Liu, MJ Abdekhodaie, XY Wu - Carbohydrate Polymers, 2010 - Elsevier
This work was intended to develop a new cross-linked gelatinized starch–xanthan gum
hydrogel system, to characterize the properties of the new material, and to explore its …

Swelling and drug release behaviour of xanthan gum matrix tablets

MM Talukdar, R Kinget - International Journal of Pharmaceutics, 1995 - Elsevier
The swelling and drug release behaviour of xanthan gum matrix tablets were studied using
three drugs having different properties, ie, caffeine as a soluble neutral drug, indomethacin …

Delivery of drugs to the lower GI tract

DR Friend, D Wong - US Patent 5,811,388, 1998 - Google Patents
Pharmaceutical compositions for orally delivering a therapeutically effective amount of a
drug to the colon without significant release of the drug in the upper GI tract after oral …

Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity

EI Lerner, V Rosenberger, M Flashner - US Patent 6,197,331, 2001 - Google Patents
4,059,686 11/1977 Tanaka et al..... 424/19 position for the oral cavity or “pharmaceutical oral
patch'4,386,106 5/1983 Merritt et al..... 426/5 that adheres to hard dental Surfaces, Such as …

Improved stability and controlled release of CLA with spray-dried microcapsules of OSA-modified starch and xanthan gum

H He, Y Hong, Z Gu, G Liu, L Cheng, Z Li - Carbohydrate polymers, 2016 - Elsevier
The objective of this investigation was to improve the stability of CLA and to allow for its
controlled release by encapsulating it with combinations of octenyl-succinic anhydride …

Evaluation of acrylamide-grafted-xanthan gum copolymer matrix tablets for oral controlled delivery of antihypertensive drugs

RC Mundargi, SA Patil, TM Aminabhavi - Carbohydrate Polymers, 2007 - Elsevier
The present study was conducted to investigate the utilization of xanthan-grafted copolymer
of acrylamide (AAm) as a controlled release (CR) matrix for antihypertensive drugs such as …

Controlled release insufflation carrier for medicaments

A Baichwal, JN Staniforth - US Patent 5,612,053, 1997 - Google Patents
The advantages of controlled release products are well known in the pharmaceutical field
and include the ability to maintain a desired blood level of a medicament over a …

Guar-based monolithic matrix systems: effect of ionizable and non-ionizable substances and excipients on gel dynamics and release kinetics

T Dürig, R Fassihi - Journal of controlled release, 2002 - Elsevier
The effect of ionic and non-ionic excipients and additives as modulators of swelling and
erosion kinetics and verapamil HCl release from guar-based matrix tablets was investigated …