Free fatty acids (FFAs) are important substrates for mitochondrial oxidative metabolism and
ATP synthesis but also cause serious stress to various tissues, contributing to the …

Energy homeostasis plays a significant role in food consumption and body weight regulation
with fat intake being an area of particular interest due to its palatability and high energy …

Background & Aims It is important to increase our understanding of gustatory detection of
dietary fat and its contribution to fat preference. We studied the roles of the fat taste receptors …

Taste receptors were first identified on the tongue, where they initiate a signaling pathway
that communicates information to the brain about the nutrient content or potential toxicity of …

Sweetness is the preferred taste of humans and many animals, likely because sugars are a
primary source of energy. In many mammals, sweet compounds are sensed in the tongue by …

With the continuous research breakthroughs on the gustatory system, special biosensors
have been developed for taste-related analyses, such as taste perception, transduction …

CD36 and two G-protein coupled receptors (GPCR), ie, GPR120 and GPR40, have been
implicated in the gustatory perception of dietary fats in rodents. These glycoproteins are …

Recent advances in the field of taste physiology have clarified the role of different basic taste
modalities and their implications in health and disease and proposed emphatically that there …

Dietary free fatty acids (FFAs), such as ω-3 fatty acids, regulate metabolic and anti-
inflammatory processes, with many of these effects attributed to FFAs interacting with a …

Bitter and sweet taste G protein-coupled receptors (known as T2Rs and T1Rs, respectively)
were originally identified in type II taste cells on the tongue, where they signal perception of …