HIV-1 receptors and cell tropism

PR Clapham, Á McKnight - British medical bulletin, 2001 - academic.oup.com
HIV virus particles interact with several receptors on cell surfaces. Two receptors, CD4 and a
co-receptor act sequentially to trigger fusion of viral and cellular membranes and confer …

Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands.

G Simmons, JD Reeves, S Hibbitts, JT Stine… - Immunological …, 2000 - europepmc.org
Human and simian immunodeficiency viruses (HIV and SIV) require a seven
transmembrane chemokine (7TM) receptor in addition to CD4 for efficient entry into cells …

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

PR Gorry, G Bristol, JA Zack, K Ritola… - Journal of …, 2001 - Am Soc Microbiol
The viral determinants that underlie human immunodeficiency virus type 1 (HIV-1)
neurotropism are unknown, due in part to limited studies on viruses isolated from brain …

Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system

TH Wang, YK Donaldson, RP Brettle, JE Bell… - Journal of …, 2001 - Am Soc Microbiol
Infection of microglia and other cells of the macrophage/monocyte lineage in the central
nervous system (CNS) by human immunodeficiency virus type I (HIV-1) underlies the …

Chemokines and receptors in HIV encephalitis

VJ Sanders, CA Pittman, MG White, G Wang, CA Wiley… - Aids, 1998 - journals.lww.com
Background: Chemokines are involved in the migration of leukocytes and have been
implicated in several inflammatory diseases of the central nervous system. Some of their …

Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design?

V Novitsky, UR Smith, P Gilbert, MF McLane… - Journal of …, 2002 - Am Soc Microbiol
An evolving dominance of human immunodeficiency virus type 1 subtype C (HIV-1C) in the
AIDS epidemic has been associated with a high prevalence of HIV-1C infection in the …

Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1

L Zhang, T He, Y Huang, Z Chen, Y Guo, S Wu… - Journal of …, 1998 - Am Soc Microbiol
We tested chemokine receptor subset usage by diverse, well-characterized primary viruses
isolated from peripheral blood by monitoring viral replication with CCR1, CCR2b, CCR3 …

Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: a set of 23 full-length clones from Botswana

VA Novitsky, MA Montano, MF McLane… - Journal of …, 1999 - Am Soc Microbiol
To better understand the virological aspect of the expanding AIDS epidemic in southern
Africa, a set of 23 near-full-length clones of human immunodeficiency virus type 1 (HIV-1) …

Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes

CM Rousseau, BA Birditt, AR McKay… - Journal of virological …, 2006 - Elsevier
Full-length HIV-1 genome sequencing provides important data needed to address several
vaccine design, molecular epidemiologic and pathogenesis questions. A protocol is …

Amplification of full-length hepatitis B virus genomes from samples from patients with low levels of viremia: frequency and functional consequences of PCR-introduced …

S Günther, G Sommer, F Von Breunig… - Journal of Clinical …, 1998 - Am Soc Microbiol
To facilitate the investigation of hepatitis B virus (HBV) sequence variation, we recently
established a method for functional analysis of PCR-amplified full-length HBV genomes …