Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases

P Chaudhary, P Janmeda, AO Docea… - Frontiers in …, 2023 - frontiersin.org
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …

Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

Cardiovascular disease in dialysis patients

M Cozzolino, M Mangano, A Stucchi… - Nephrology Dialysis …, 2018 - academic.oup.com
Cardiovascular disease (CVD) is a highly common complication and the first cause of death
in patients with end-stage renal disease (ESRD) on haemodialysis (HD). In this population …

Chronic kidney disease as oxidative stress-and inflammatory-mediated cardiovascular disease

A Podkowińska, D Formanowicz - Antioxidants, 2020 - mdpi.com
Generating reactive oxygen species (ROS) is necessary for both physiology and pathology.
An imbalance between endogenous oxidants and antioxidants causes oxidative stress …

Inflammation and oxidative stress in chronic kidney disease—potential therapeutic role of minerals, vitamins and plant-derived metabolites

SF Rapa, BR Di Iorio, P Campiglia, A Heidland… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …

Oxidative stress in the pathogenesis and evolution of chronic kidney disease: untangling Ariadne's thread

A Duni, V Liakopoulos, S Roumeliotis… - International journal of …, 2019 - mdpi.com
Amplification of oxidative stress is present since the early stages of chronic kidney disease
(CKD), holding a key position in the pathogenesis of renal failure. Induction of renal pro …

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia

J Voelkl, F Lang, KU Eckardt, K Amann… - Cellular and Molecular …, 2019 - Springer
Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …

Chronic kidney disease as a systemic inflammatory syndrome: update on mechanisms involved and potential treatment

F Tinti, S Lai, A Noce, S Rotondi, G Marrone… - Life, 2021 - mdpi.com
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving
systemic organs and apparatus, associated with elevated cardiovascular morbidity and …

Oxidative stress in ESRD patients on dialysis and the risk of cardiovascular diseases

J Rysz, B Franczyk, J Ławiński, A Gluba-Brzózka - Antioxidants, 2020 - mdpi.com
Chronic kidney disease is highly prevalent worldwide. The decline of renal function is
associated with inadequate removal of a variety of uremic toxins that exert detrimental …

Malnutrition in chronic kidney disease

FM Iorember - Frontiers in pediatrics, 2018 - frontiersin.org
Patients with chronic kidney disease are at substantial risk for malnutrition, characterized by
protein energy wasting and micronutrient deficiency. Studies show a high prevalence rate of …