Background Substantial evidence suggests that cognitive deficits might persist after
remission of a major depressive episode. However, results are inconsistent relative to the …

Major depression is the commonest psychiatric disorder and in the US has the greatest
impact of all biomedical diseases on disability. Here we review evidence of the genetic …

Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

In this Seminar we discuss developments from the past 5 years in the diagnosis,
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …

The British Association for Psychopharmacology guidelines specify the scope and targets of
treatment for bipolar disorder. The third version is based explicitly on the available evidence …

Background Mood disorders (including major depressive disorder and bipolar disorder)
affect 10% to 20% of the population. They range from brief, mild episodes to severe …

Abstract The British Association for Psychopharmacology guidelines specify the scope and
target of treatment for bipolar disorder. The second version, like the first, is based explicitly …

Disruptions in circadian rhythms have been described in mood disorders (MD), but the
involvement of genetic variation in genes pertaining to the molecular circadian machinery in …

Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …

OBJECTIVE: To determine the rate of diagnostic conversion from an operationalized
diagnosis of bipolar disorder not otherwise specified (BP-NOS) to bipolar I disorder (BP-I) or …