A growing understanding of the benefits of exercise over the past few decades has
prompted researchers to take an interest in the possibilities of exercise therapy. Because …

Physical activity (PA) has been central in the life of our species for most of its history, and
thus shaped our physiology during evolution. However, only recently the health …

We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in
the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum …

Background: A number of studies evaluating physical therapy and exercise interventions in
Huntington's disease have been conducted over the past 15 years. However, an …

Huntington disease (HD) is an autosomal dominant neurodegenerative disease that is
caused by expansion of cytosine/adenosine/guanine repeats in the huntingtin (HTT) gene …

Objective In the past decade, an increasing number of studies have examined the efficacy of
physical therapy interventions in people with Huntington disease (HD). Methods We …

Cognitive impairment is prevalent in Huntington's disease (HD), with no treatments currently
available. While cognition-oriented treatments and physical exercise have shown efficacy in …

Objective The aim of this phase 2 trial was to ascertain the feasibility and effect of community-
based aerobic exercise training for people with 2 of the more common neuromuscular …

While Huntington disease (HD) is caused solely by a polyglutamine expansion in the
huntingtin gene, environmental factors can influence HD onset and progression. Here, we …