Bursting microbubbles: How nanobubble contrast agents can enable the future of medical ultrasound molecular imaging and image-guided therapy

AA Exner, MC Kolios - Current opinion in colloid & interface science, 2021 - Elsevier
The field of medical ultrasound has undergone a significant evolution since the development
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …

Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations

AJ Sojahrood, Q Li, H Haghi, R Karshafian… - Ultrasonics …, 2023 - Elsevier
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …

Nonlinear dynamics of acoustic bubbles excited by their pressure-dependent subharmonic resonance frequency: influence of the pressure amplitude, frequency …

AJ Sojahrood, R Earl, H Haghi, Q Li, TM Porter… - Nonlinear …, 2021 - Springer
Nonlinear behavior of bubbles, and most importantly 1 2 1 2-order subharmonics (SH), are
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …

[HTML][HTML] Effects of medium viscoelasticity on bubble collapse strength of interacting polydisperse bubbles

D Qin, Q Zou, X Zhong, B Zhang, Z Li - Ultrasonics Sonochemistry, 2023 - Elsevier
Due to its physical and/or chemical effects, acoustic cavitation plays a crucial role in various
emerging applications ranging from advanced materials to biomedicine. The cavitation …

Nanobubble Contrast Enhanced Ultrasound Imaging: A Review

D Wegierak, P Nittayacharn, MB Cooley… - Wiley …, 2024 - Wiley Online Library
Contrast‐enhanced ultrasound is currently used worldwide with clinical indications in
cardiology and radiology, and it continues to evolve and develop through innovative …

[HTML][HTML] Resonance behaviors of encapsulated microbubbles oscillating nonlinearly with ultrasonic excitation

D Qin, S Lei, X Wang, X Zhong, X Ji, Z Li - Ultrasonics Sonochemistry, 2023 - Elsevier
The resonance behaviors of a few lipid-coated microbubbles acoustically activated in
viscoelastic media were comprehensively examined via radius response analysis. The size …

[HTML][HTML] Nonlinear dynamics and acoustic emissions of interacting cavitation bubbles in viscoelastic tissues

D Qin, Q Zou, S Lei, W Wang, Z Li - Ultrasonics Sonochemistry, 2021 - Elsevier
The cavitation-mediated bioeffects are primarily associated with the dynamic behaviors of
bubbles in viscoelastic tissues, which involves complex interactions of cavitation bubbles …

Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …

AJ Sojahrood, H Haghi, R Karshafian, MC Kolios - Physics of Fluids, 2021 - pubs.aip.org
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …

[HTML][HTML] Nonlinear dynamics and bifurcation structure of ultrasonically excited lipid coated microbubbles

AJ Sojahrood, H Haghi, R Karshafian… - Ultrasonics Sonochemistry, 2021 - Elsevier
In many applications, microbubbles (MBs) are encapsulated by a lipid coating to increase
their stability. However, the complex behavior of the lipid coating including buckling and …

[HTML][HTML] Nonlinear power loss in the oscillations of coated and uncoated bubbles: Role of thermal, radiation and encapsulating shell damping at various excitation …

AJ Sojahrood, H Haghi, Q Li, TM Porter… - Ultrasonics …, 2020 - Elsevier
This study presents the fundamental equations governing the pressure dependent disipation
mechanisms in the oscillations of coated bubbles. A simple generalized model (GM) for …