Physico‐chemical properties, pharmacokinetics, molecular docking and in‐vitro pharmacological study of a cobalt (II) complex based on 2‐aminopyridine

N Mhadhbi, N Issaoui, WS Hamadou, JM Alam… - …, 2022 - Wiley Online Library
The organic‐inorganic hybrid compound (2‐HAP) 2 [CoBr4],(2‐HAP= 2‐protonated
aminopyridinium cation) was characterized by various physicochemical techniques …

Expression profiling of selected immune genes and trabecular microarchitecture in breast cancer skeletal metastases model: Effect of α–tocopherol acetate …

R Badraoui, M Saeed, N Bouali, WS Hamadou… - Calcified Tissue …, 2022 - Springer
Breast cancer bone metastases (BCBM) result in serious skeletal morbidity. Although there
have been important advances in cancer treatment methods such as surgery and …

Unveiling the Potential of Algal Extracts as Promising Antibacterial and Antibiofilm Agents against Multidrug-Resistant Pseudomonas aeruginosa: In Vitro and In Silico …

S El-Sapagh, R El-Shenody, L Pereira, M Elshobary - Plants, 2023 - mdpi.com
Multidrug-resistant Pseudomonas aeruginosa poses a global challenge due to its virulence
and biofilm-forming ability, leading to persistent infections. This study had a dual focus: first …

Molecular interactions of polyvinyl chloride microplastics and beta-blockers (Diltiazem and Bisoprolol) and their effects on marine meiofauna: Combined in vivo and …

M Allouche, S Ishak, MB Ali, A Hedfi, M Almalki… - Journal of Hazardous …, 2022 - Elsevier
The ecotoxicological effects of beta-blockers (ie Diltiazem and Bisoprolol) and their
interactions with the microplastic polyvinyl chloride on marine meiofauna were tested in …

Attenuation of ovalbumin-induced inflammation and lung oxidative injury in asthmatic rats by Zingiber officinale extract: combined in silico and in vivo study on antioxidant …

O Jedli, H Ben-Nasr, N Zammel, T Rebai, M Saoudi… - 3 Biotech, 2022 - Springer
In the present study we focused on the anti-asthmatic and antioxidant effects of Zingiber
officinalis roscoe L.(ZO) aqueous extract. This study includes 20 adult male rats, which were …

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on …

I Bédoui, HB Nasr, K Ksouda, W Ayadi… - Pharmacognosy …, 2024 - journals.sagepub.com
Background Finding new effective substances to develop drugs against cancer or to prevent
it remains a big challenge facing scientists and clinicians. Objectives In such an issue, we …

Ethnopharmacology and ethnopharmacognosy: current perspectives and future prospects

R Badraoui, AJ Siddiqui, F Bardakci… - … of Medicinal and …, 2023 - taylorfrancis.com
Ethnopharmacology is more than a simple study of medicinal plants used in traditional
cultures. It is categorized as an interdisciplinary scientific investigation of biologically active …

Chemical Composition and the Anticancer, Antimicrobial, and Antioxidant Properties of Acacia Honey from the Hail Region: The in vitro and in silico Investigation

WS Hamadou, N Bouali, R Badraoui… - Evidence‐Based …, 2022 - Wiley Online Library
In consideration of the emergence of novel drug‐resistant microbial strains and the increase
in the incidences of various cancers throughout the world, honey could be utilized as a great …

Antiviral effects of artemisinin and its derivatives against SARS-CoV-2 main protease: Computational evidences and interactions with ACE2 allelic variants

R Badraoui, M Saoudi, WS Hamadou, S Elkahoui… - Pharmaceuticals, 2022 - mdpi.com
Fighting against the emergent coronavirus disease (COVID-19) remains a big challenge at
the front of the world communities. Recent research has outlined the potential of various …

Phytochemical Analysis, Antioxidant, Antimicrobial, and Anti‐Swarming Properties of Hibiscus sabdariffa L. Calyx Extracts: In Vitro and In Silico Modelling …

B Hamrita, N Emira, A Papetti… - Evidence‐Based …, 2022 - Wiley Online Library
The aim of this study was to investigate the phytochemical composition of dried Roselle
calyx (Hibiscus sabdariffa L.) using both ethanolic and aqueous extracts. We report the …