Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …

Survivin is a member of the inhibitor-of-apoptosis proteins (IAPs) family; its overexpression
has been widely demonstrated to occur in various types of cancer. Overexpression of …

Breast cancer in young women is more aggressive with a poorer prognosis and overall
survival compared to older women diagnosed with the disease. Despite recent research, the …

Colorectal cancer is the third most common diagnosed cancer globally. Although substantial
advances have been obtained both in treatment and survival rates, there is still a need for …

Breast cancer is one of the common tumors occurring in woman and despite treatment, the
prognostic is poor. Genistein, a soy isoflavone, has been reported to have chemopreventive …

Impairment of the p53 pathway is a critical event in cancer. Therefore, reestablishing p53
activity has become one of the most appealing anticancer therapeutic strategies. Here, we …

Nicotinamide phosphorybosiltransferase (NAMPT) plays an important role in the regulation
of cellular growth, angiogenesis, and apoptosis in mammalian cells. NAMPT overexpression …

Background. Denticleless E3 ubiquitin protein ligase homolog (DTL) has been reported to
be an important regulator for tumorigenesis and progression. Nonetheless, the biological …

The heterogeneous group of diseases collectively termed cancer results not just from
aberrant cellular proliferation but also from a lack of accompanying homeostatic cell death …

Osteosarcoma (OS) is a malignant tumor originating from primitive mesenchymal tissue that
occurs mostly in children and adolescents. It is the most common type of malignant tumor …