Harnessing artificial intelligence for the next generation of 3D printed medicines

M Elbadawi, LE McCoubrey, FKH Gavins… - Advanced Drug Delivery …, 2021 - Elsevier
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …

[HTML][HTML] Polymers in pharmaceutical additive manufacturing: A balancing act between printability and product performance

R Govender, EO Kissi, A Larsson, I Tho - Advanced Drug Delivery Reviews, 2021 - Elsevier
Materials and manufacturing processes share a common purpose of enabling the
pharmaceutical product to perform as intended. This review on the role of polymeric …

Importance of polymer rheology on material extrusion additive manufacturing: correlating process physics to print properties

A Das, EL Gilmer, S Biria… - ACS Applied Polymer …, 2021 - ACS Publications
Recent advances in the field of additive manufacturing (AM) or 3D printing, have garnered
serious interest for its potential to substitute time-consuming and costly subtractive and …

Designing 3D printable polypropylene: Material and process optimisation through rheology

M Bertolino, D Battegazzore, R Arrigo, A Frache - Additive Manufacturing, 2021 - Elsevier
A polypropylene-based material has been formulated to be suitable for fused deposition
modelling (FDM). In fact, the high volumetric shrinkage and the rheological behaviour are …

3D printing tablets: Predicting printability and drug dissolution from rheological data

M Elbadawi, T Gustaffson, S Gaisford… - International Journal of …, 2020 - Elsevier
Rheology is an indispensable tool for formulation development, which when harnessed, can
both predict a material's performance and provide valuable insight regarding the material's …

Pressure-assisted microsyringe 3D printing of oral films based on pullulan and hydroxypropyl methylcellulose

M Elbadawi, D Nikjoo, T Gustafsson, S Gaisford… - International Journal of …, 2021 - Elsevier
Oral films (OFs) continue to attract attention as drug delivery systems, particularly for pedatric
and geriatric needs. However, immiscibility between different polymers limits the full …

Fused deposition modelling (FDM) of thermoplastic-based filaments: process and rheological properties—an overview

D Acierno, A Patti - Materials, 2023 - mdpi.com
The fused deposition modeling (FDM) process, an extrusion-based 3D printing technology,
enables the manufacture of complex geometrical elements. This technology employs …

Machine learning and machine vision accelerate 3D printed orodispersible film development

CS O'Reilly, M Elbadawi, N Desai, S Gaisford… - Pharmaceutics, 2021 - mdpi.com
Orodispersible films (ODFs) are an attractive delivery system for a myriad of clinical
applications and possess both large economical and clinical rewards. However, the …

Enhancement of 3D printability by FDM and electrical conductivity of PLA/MWCNT filaments using lignin as bio-dispersant

S Lage-Rivera, A Ares-Pernas, JC Becerra Permuy… - Polymers, 2023 - mdpi.com
To increase the applications of FDM (fusion deposition modeling) 3D printing in electronics,
it is necessary to develop new filaments with good electrical properties and suitable …

The influence of pregelatinized starch on the rheology of a gellan gum-collagen IPN hydrogel for 3D bioprinting

JY Ng, P Yu, DM Murali, YS Liu, R Gokhale… - … Research and Design, 2023 - Elsevier
Hydrogel scaffolds infused with stem cells are valuable alternatives to skin grafts in
replacement of lost host tissues. In a prior study, we developed an adipose-derived stem …