The frontier of live tissue imaging across space and time

Q Huang, A Garrett, S Bose, S Blocker, AC Rios… - Cell Stem Cell, 2021 - cell.com
What you see is what you get—imaging techniques have long been essential for
visualization and understanding of tissue development, homeostasis, and regeneration …

State-of-the-art challenges and emerging technologies in radiation detection for nuclear medicine imaging: A review

E Enlow, S Abbaszadeh - Frontiers in Physics, 2023 - frontiersin.org
Single photon emission computed tomography (SPECT) and positron emission tomography
(PET) are established medical imaging modalities that have been implemented for decades …

Evolution of PET detectors and event positioning algorithms using monolithic scintillation crystals

A Gonzalez-Montoro, AJ Gonzalez… - … on Radiation and …, 2021 - ieeexplore.ieee.org
The use of monolithic scintillator-based photon detectors in positron emission tomography
(PET) has emerged as an attractive alternative to traditional pixelated array designs …

Submillimeter-resolution PET for high-sensitivity mouse brain imaging

HG Kang, H Tashima, H Wakizaka… - Journal of Nuclear …, 2023 - Soc Nuclear Med
PET is a powerful molecular imaging technique that can provide functional information on
living objects. However, the spatial resolution of PET imaging has been limited to around 1 …

Photon counting detectors and their applications ranging from particle physics experiments to environmental radiation monitoring and medical imaging

R Ota - Radiological Physics and Technology, 2021 - Springer
Photomultiplier tubes (PMTs) and silicon photomultipliers (SiPMs) have played essential
roles in various applications, such as fundamental particle physics experiments, nuclear …

[HTML][HTML] Detectors in positron emission tomography

A Zatcepin, SI Ziegler - Zeitschrift für Medizinische Physik, 2023 - Elsevier
Positron emission tomography is a highly sensitive molecular imaging modality, based on
the coincident detection of annihilation photons after positron decay. The most used detector …

Recent technical advances in accelerating the clinical translation of small animal brain imaging: hybrid imaging, deep learning, and transcriptomics

W Ren, B Ji, Y Guan, L Cao, R Ni - Frontiers in Medicine, 2022 - frontiersin.org
Small animal models play a fundamental role in brain research by deepening the
understanding of the physiological functions and mechanisms underlying brain disorders …

Advances in preclinical PET

SS Adler, J Seidel, PL Choyke - Seminars in nuclear medicine, 2022 - Elsevier
The classical intent of PET imaging is to obtain the most accurate estimate of the amount of
positron-emitting radiotracer in the smallest possible volume element located anywhere in …

Application of advanced imaging modalities in veterinary medicine: a review

D Yitbarek, GG Dagnaw - Veterinary Medicine: Research and …, 2022 - Taylor & Francis
Veterinary anatomy has traditionally relied on detailed dissections to produce anatomical
illustrations, but modern imaging modalities, now represent an enormous resource that …

H2RSPET: a 0.5 mm resolution high-sensitivity small-animal PET scanner, a simulation study

Y Lai, Q Wang, S Zhou, Z Xie, J Qi… - Physics in Medicine …, 2021 - iopscience.iop.org
With the goal of developing a total-body small-animal PET system with a high spatial
resolution of∼ 0.5 mm and a high sensitivity> 10% for mouse/rat studies, we simulated four …