The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Aspiration pneumonia

LA Mandell, MS Niederman - New England Journal of Medicine, 2019 - Mass Medical Soc
Aspiration Pneumonia | NEJM Skip to main content NEJM Group Follow Us Facebook Twitter
Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge, lead a …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence

D Focosi, F Maggi, A Casadevall - Viruses, 2022 - mdpi.com
Sterilizing immunity after vaccination is desirable to prevent the spread of infection from
vaccinees, which can be especially dangerous in hospital settings while managing frail …

Clinical features and outcomes of discharged coronavirus disease 2019 patients: a prospective cohort study

X Wang, H Xu, H Jiang, L Wang, C Lu… - … Journal of Medicine, 2020 - academic.oup.com
Summary Background Coronavirus disease 2019 (COVID-19) is a global pandemic but the
follow-up data of discharged patients was barely described. Aim To investigate clinical …

Immunity to invasive fungal diseases

A Casadevall - Annual review of immunology, 2022 - annualreviews.org
Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

Disease tolerance as a defense strategy

R Medzhitov, DS Schneider, MP Soares - Science, 2012 - science.org
The immune system protects from infections primarily by detecting and eliminating the
invading pathogens; however, the host organism can also protect itself from infectious …

The virulence of Streptococcus mutans and the ability to form biofilms

W Krzyściak, A Jurczak, D Kościelniak… - European Journal of …, 2014 - Springer
In some diseases, a very important role is played by the ability of bacteria to form multi-
dimensional complex structure known as biofilm. The most common disease of the oral …

Cryptosporidium pathogenicity and virulence

M Bouzid, PR Hunter, RM Chalmers… - Clinical microbiology …, 2013 - Am Soc Microbiol
Cryptosporidium is a protozoan parasite of medical and veterinary importance that causes
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …

The complex relationship between virulence and antibiotic resistance

M Schroeder, BD Brooks, AE Brooks - Genes, 2017 - mdpi.com
Antibiotic resistance, prompted by the overuse of antimicrobial agents, may arise from a
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …