Therapeutic advancement of chronic lymphocytic leukemia

K Lu, X Wang - Journal of hematology & oncology, 2012 - Springer
Despite the combinations of chemotherapy with monoclonal antibodies have further
improved response rates, chronic lymphocytic leukemia (CLL) remains an incurable disease …

[HTML][HTML] Long-term studies assessing outcomes of ibrutinib therapy in patients with del (11q) chronic lymphocytic leukemia

TJ Kipps, G Fraser, SE Coutre, JR Brown… - … Myeloma and Leukemia, 2019 - Elsevier
Background Certain genomic features, such as del (11q), expression of unmutated
immunoglobulin heavy-chain variable region (IGHV) gene, or complex karyotype, predict …

Current status of haematopoietic autologous stem cell transplantation in lymphoid malignancies: a European perspective

K Hübel, J de la Rubia, N Azar… - European Journal of …, 2015 - Wiley Online Library
The use of autologous haematopoietic stem cell transplantation (ASCT) has increased
considerably in lymphoid malignancies in the last decade, and it is now considered as the …

Time trends in primary therapy and relative survival of diffuse large B-cell lymphoma by stage: a nationwide, population-based study in the Netherlands, 1989–2018

M Durmaz, O Visser, EFM Posthuma, RE Brouwer… - Blood cancer …, 2022 - nature.com
It is unclear whether survival in diffuse large B-cell lymphoma (DLBCL) continues to
increase in an era where rituximab-containing chemotherapy reigns for almost two decades …

Impact of drug development on the use of stem cell transplantation: a report by the European Society for Blood and Marrow Transplantation (EBMT)

JR Passweg, H Baldomero, P Bader, C Bonini… - Bone marrow …, 2017 - nature.com
Hematopoietic stem cell transplantation (HSCT) is used with increasing frequency in Europe
with 40 000 transplants reported in 2014. Transplant-related mortality remains high in …

Pharmacological management of chronic lymphocytic leukemia: current and emerging therapies

IJ Huang, GT Baek, C Siu… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL),
characterized by its monoclonal lymphoproliferative nature, is an indolent but incurable …

Pentostatin, cyclophosphamide, and rituximab followed by alemtuzumab for relapsed or refractory chronic lymphocytic leukemia: a phase 2 trial of the ECOG-Acrin …

S Kempin, Z Sun, NE Kay, EM Paietta, JJ Mazza… - Acta …, 2019 - karger.com
Patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) may benefit from
salvage chemoimmunotherapy (CIT). To explore further the use of CIT in the pre-novel agent …

The evolving role of stem cell transplantation in chronic lymphocytic leukemia

P Dreger - Hematology/Oncology Clinics, 2013 - hemonc.theclinics.com
To improve the prognosis of patients with poor-risk chronic lymphocytic leukemia (CLL),
efforts to develop effective treatment strategies have focused on autologous and allogeneic …

Immunotherapeutic strategies including transplantation: eradication of disease

JG Gribben, JC Riches - Hematology 2013, the American …, 2013 - ashpublications.org
Although there have been recent advances with targeted therapies in chronic lymphocytic
leukemia (CLL), chemoimmunotherapy remains the treatment of choice; however, this …

Changes in the diagnosis and treatment of patients with low grade lymphoma in Germany: years 2006–2009

C Schmidt, G Fingerle-Rowson, A Boehme… - Leukemia & …, 2015 - Taylor & Francis
Today's treatment options for indolent lymphoma and chronic lymphocytic leukemia (CLL)
range from watch & wait, immunochemotherapy up to allogeneic transplantation. We …