The aim of the study was to investigate the impact of erlotinib sulfobutyl ether beta-
cyclodextrin complex (ERL-SBE-β-CD) on ERL dissolution rate and oral bioavailability …

Mansonone G (MG), a plant-derived compound isolated from the heartwood of Mansonia
gagei, possesses a potent antitumor effect on several kinds of malignancy. However, its poor …

Emodin (ED), one prominent variant of naturally occurring anthraquinones traditionally used
in Chinese medicine, exhibits a wide spectrum of pharmacological properties. However, the …

Agomelatine (AGM), is efficacious in both the acute phase and the continuation phase of
depression. However, its poor water-solubility, low bioavailability and polymorphism limit its …

Abstract Drug-in-cyclodextrin-in-liposome (DCL) combines advantages of cyclodextrin and
liposome. Here, DCL formulation was successfully prepared to encapsulate limonene (Lim) …

Benznidazole (BNZ) is the drug of choice for Chagas disease treatment, which affects about
9.8 million people worldwide. It has low solubility and high toxicity. The present study aimed …

The study of antioxidants and radicals has always been a complex task due to the special
characteristics of these species such as reactions at low concentrations and short half–lives …

A series of ferrocenyl hydrazones and their β-cyclodextrin (CD) inclusion complexes were
prepared and evaluated for antitubercular activity under low and high iron conditions. The …

Efavirenz (EFZ) is one of the most used drugs in the treatment of AIDS and is the first
antiretroviral choice. However, since it has low solubility, it does not exhibit suitable …

The inclusion complex of ceftazidime (CF) with hydroxypropyl-γ-cyclodextrin (HP-γ-CD) was
prepared. The inclusion behavior and interactions of CF with HP-γ-CD was carried out in …