The localization of RNAs critically contributes to many important cellular processes in an
organism, such as the establishment of polarity, asymmetric division and migration during …

Localization of RNA is a widespread and efficient way to target gene products to a specific
region of a cell or embryo. This strategy of posttranscriptional gene regulation utilizes a …

Riboswitches are intricate, metabolite-binding RNA structures found in the non-coding
regions of mRNA. Allosteric changes in the riboswitch that are induced by metabolite …

In yeast Saccharomyces cerevisiae, Ash1p, a protein determinant for mating-type switching,
is segregated within the daughter cell nucleus to establish asymmetry of HO expression. The …

In eukaryotes, the entwined pathways of RNA transport and local translational regulation are
key determinants in the spatio-temporal articulation of gene expression. One of the main …

Asymmetric subcellular distribution of RNA is used by many organisms to establish cell
polarity, differences in cell fate, or to sequester protein activity. Accurate localization of RNA …

▪ Abstract The intracellular localization of mRNA, a common mechanism for targeting
proteins to specific regions of the cell, probably occurs in most if not all polarized cell types …

Staufen1 is a component of transported ribonucleoprotein complexes. Genetic work in
Drosophila has suggested that Staufen plays a role in the de-repression of translation of …

In S. cerevisiae, the ASH1 mRNA is localized at the bud tip of late-anaphase cells, resulting
in the exclusive sorting of Ash1p to the daughter cell nucleus. While the mechanism behind …

Active cytoplasmic RNA localization depends on the attachment of RNA-binding proteins
that dictate the destination of the RNA molecule. In this study, we used an electrophoretic …