An estimated 30–40% of cancers can be prevented through changes in modifiable lifestyle
and environmental risk factors known to be associated with cancer incidence. Despite this …

Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Physical activity can treat and prevent depressive symptoms, but its antidepressant
mechanisms are yet to be established. In this review, we comprehensively assess key …

The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Despite the physiological role of oxidant molecules, oxidative stress (OS) could underlie
several human diseases. When the levels of antioxidants are too low or too high, OS occurs …

Extracellular superoxide dismutase (EcSOD) is the only extracellular scavenger of
superoxide anion (O 2.-) with unique binding capacity to cell surface and extracellular matrix …

Background Depression and anxiety are the leading mental health problems worldwide;
depression is ranked as the leading cause of global disability with anxiety disorders ranked …

Increasing evidence indicates that exercise has beneficial effects on chronic inflammation,
cardiorespiratory function, muscle and bone strength and metabolic markers in adults with …