Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer,
ranks among the leading causes of cancer-related deaths in the Western world due to …

Pancreatic cancer remains a lethal malignancy with poor prognosis owing to therapeutic
resistance, frequent recurrence and the absence of treatment strategies that specifically …

Mucins (MUC) are high molecular weight O-linked glycoproteins whose primary functions
are to hydrate, protect, and lubricate the epithelial luminal surfaces of the ducts within the …

Pancreatic ductal adenocarcinoma (PDA) ranks fourth among cancer related deaths. The
disappointing 5-year survival rate of below 5% stems from drug resistance to all known …

Pancreatic tumors are resistant to conventional chemotherapies. The present study was
aimed at evaluating the potential of a novel plant-derived product as a therapeutic agent for …

Pancreatic ductal adenocarcinoma, an exocrine tumor, is the most common type of cancer of
the pancreas and one of the top five most prominent causes of cancer-associated mortality …

Mucins are a family of multifunctional glycoproteins that mostly line the surface of epithelial
cells in the gastrointestinal tract and exert pivotal roles in gut lubrication and protection …

Mucins are high molecular weight, multifunctional glycoproteins comprised of two structural
classes—the large transmembrane mucins and the gel-forming or secreted mucins. The …

The fluorinated analog of deoxycytidine, Gemcitabine (Gemzar), is the main
chemotherapeutic drug in pancreatic cancer, but survival remains weak mainly because of …

Pancreatic cancer is one of the most lethal cancers in the world, as it continues to be
resistant to any therapeutic approaches. The high molecular weight glycoprotein mucin 4 …