Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

Major depression, with its strikingly high prevalence, is the most common cause of disability
in communities of Western type, according to data of the World Health Organization. Stress …

The locus coeruleus (LC) is a small nucleus in the pons from which ascending and
descending projections innervate major parts of the central nervous system. Its major …

Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …

TRH is a tripeptide amide that functions as a neurotransmitter but also serves as a
neurohormone that has a critical role in the central regulation of the hypothalamic-pituitary …

A fundamental question of physiology is how gut-brain signaling stimulates appetite. While
many studies have emphasized the importance of vagal afferents to the brain in inducing …

Environmental stimuli that signal real or potential threats to homeostasis lead to
glucocorticoid secretion by the hypothalamic–pituitary–adrenocortical (HPA) axis …

The Dual Center Model for Regulation of Feeding paraventricular nucleus is a major source
of input to the Most neuroscientists have grown up with the classic sympathetic and …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

In addition to a nonadecapeptide homologous to the teleost melanin‐concentrating
hormone (MCH), the amino acid sequence predicted from a rat prepro‐MCH (ppMCH) cDNA …