Artificial pancreas: past, present, future

C Cobelli, E Renard, B Kovatchev - Diabetes, 2011 - Am Diabetes Assoc
The artificial pancreas (AP), known as closed-loop control of blood glucose in diabetes, is a
system combining a glucose sensor, a control algorithm, and an insulin infusion device. AP …

Mathematical models and software tools for the glucose-insulin regulatory system and diabetes: an overview

A Makroglou, J Li, Y Kuang - Applied numerical mathematics, 2006 - Elsevier
An overview of some of the mathematical models appearing in the literature for use in the
glucose-insulin regulatory system in relation to diabetes is given, enhanced with a survey on …

Closed loop system for controlling insulin infusion

GM Steil, K Rebrin, PV Goode Jr… - US Patent …, 2003 - Google Patents
CA (US) Parker, Robert S., et al.,“The Intravenous Route to Blood Glucose Control”, IEEE
Engineering in Medicine and Biol-(*) Notice: Subject to any disclaimer, the term of this ogy …

Closed-loop method for controlling insulin infusion

GM Steil, K Rebrin - US Patent 7,402,153, 2008 - Google Patents
4.280, 494 A* 7, 1981 Cosgrove et al............. 604,503 4,291,692 A* 9/1981 Bowman et al....
604/31 4,786,394 A 11, 1988 Enzer et al. 5,050,612 A 9, 1991 Matsumura 5,068,536 A 11 …

Method and system for providing sensor redundancy

JJ Mastrototaro, RK Yoon, DB Keenan - US Patent 7,946,985, 2011 - Google Patents
A closed loop system or semi-closed loop system for infusing insulin using sensor values
applies a redundant sensor system as a fail-safe method against sensor failure. The …

In Silico Preclinical Trials: A Proof of Concept in Closed-Loop Control of Type 1 Diabetes

BP Kovatchev, M Breton, C Dalla Man, C Cobelli - 2009 - journals.sagepub.com
Arguably, a minimally invasive system using subcutaneous (sc) continuous glucose
monitoring (CGM) and sc insulin delivery via insulin pump would be a most feasible step to …

Closed loop system for controlling insulin infusion

GM Steil, K Rebrin - US Patent 7,267,665, 2007 - Google Patents
(57) ABSTRACT A closed loop infusion system controls the rate that? uid is infused into the
body of a user. The closed loop infusion system includes a sensor system, a controller, and …

Method, system, and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data

BP Kovatchev, DJ Cox - US Patent 7,025,425, 2006 - Google Patents
US7025425B2 - Method, system, and computer program product for the evaluation of
glycemic control in diabetes from self-monitoring data - Google Patents US7025425B2 …

Methods for estimating analyte-related signals, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices …

SP Desai, TC Dunn, MJ Lesho, RO Potts… - US Patent …, 2010 - Google Patents
The present invention relates to methods to increase the number of analyte-related signals
used to provide analyte measurement values, eg, when two or more analyte-related signals …

Method, system, and computer program product for the processing of self-monitoring blood glucose (SMBG) data to enhance diabetic self-management

BP Kovatchev, DJ Cox - US Patent 8,538,703, 2013 - Google Patents
US8538703B2 - Method, system, and computer program product for the processing of self-monitoring
blood glucose(SMBG)data to enhance diabetic self-management - Google Patents …