The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with
increased health expenditure, and low quality of life. Many non-genetic risk factors have …

Background To systematically review the epidemiologic relationship between periodontitis
and type 2 diabetes mellitus (T2DM). Methods Four electronic databases were searched up …

The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to
the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular …

Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …

Aims There has been growing evidence that adiponectin, tumor necrosis factor-α (TNF-α)
and inflammatory cytokines involved in insulin resistance and may be attractive candidates …

Obesity is a worldwide pandemic in adults as well as children and adds greatly to health
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …