Kawasaki disease: etiopathogenesis and novel treatment strategies

S Agarwal, DK Agrawal - Expert review of clinical immunology, 2017 - Taylor & Francis
Introduction: Kawasaki disease is an acute febrile systemic vasculitis that predominantly
occurs in children below five years of age. Its etiopathogenesis is still not clear, but it is …

[HTML][HTML] IL-1 inhibitors in the treatment of monogenic periodic fever syndromes: from the past to the future perspectives

H Malcova, Z Strizova, T Milota, I Striz… - Frontiers in …, 2021 - frontiersin.org
Autoinflammatory diseases (AIDs) represent a rare and heterogeneous group of disorders
characterized by recurrent episodes of inflammation and a broad range of clinical …

[HTML][HTML] Unveiling the efficacy, safety, and tolerability of anti-interleukin-1 treatment in monogenic and multifactorial autoinflammatory diseases

A Bettiol, G Lopalco, G Emmi, L Cantarini… - International journal of …, 2019 - mdpi.com
Autoinflammatory diseases (AIDs) are heterogeneous disorders characterized by
dysregulation in the inflammasome, a large intracellular multiprotein platform, leading to …

The CXCL10/CXCR3 axis and cardiac inflammation: implications for immunotherapy to treat infectious and noninfectious diseases of the heart

R Altara, Z Mallat, GW Booz… - Journal of immunology …, 2016 - Wiley Online Library
Accumulating evidence reveals involvement of T lymphocytes and adaptive immunity in the
chronic inflammation associated with infectious and noninfectious diseases of the heart …

[HTML][HTML] Infliximab versus intravenous immunoglobulin for refractory Kawasaki disease: a phase 3, randomized, open-label, active-controlled, parallel-group …

M Mori, T Hara, M Kikuchi, H Shimizu, T Miyamoto… - Scientific reports, 2018 - nature.com
We compared the efficacy and safety of infliximab with intravenous immunoglobulin (IVIG), a
standard therapy, in a phase 3 trial (NCT01596335) for Japanese patients with Kawasaki …

Predicting Coronary Artery Aneurysms in Kawasaki Disease at a North American Center: An Assessment of Baseline z Scores

MBF Son, K Gauvreau, S Kim, A Tang… - Journal of the …, 2017 - Am Heart Assoc
Background Accurate risk prediction of coronary artery aneurysms (CAAs) in North American
children with Kawasaki disease remains a clinical challenge. We sought to determine the …

[HTML][HTML] Interleukin-1 blockade in polygenic autoinflammatory disorders: where are we now?

H Malcova, T Milota, Z Strizova… - Frontiers in …, 2021 - frontiersin.org
Polygenic autoinflammatory diseases (AIDs), such as systemic juvenile idiopathic arthritis
(sJIA), adult-onset Still's disease, Kawasaki disease, idiopathic recurrent pericarditis (IRP) …

[HTML][HTML] Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysis

Y Kimura, M Yanagimachi, Y Ino, M Aketagawa… - Scientific reports, 2017 - nature.com
Kawasaki disease (KD) is a systemic vasculitis and childhood febrile disease that can lead
to cardiovascular complications. The diagnosis of KD depends on its clinical features, and …

Subclinical cardiac dysfunction in polymyositis and dermatomyositis: a speckle-tracking case-control study

F Guerra, C Gelardi, A Capucci, A Gabrielli… - The Journal of …, 2017 - jrheum.org
Objective. Subclinical heart disease occurs in up to 50% of patients with idiopathic
inflammatory myopathies (IIM) and is difficult to detect through conventional imaging. We …

The role of corticosteroids in the treatment of Kawasaki disease

LS Chang, HC Kuo - Expert review of anti-infective therapy, 2020 - Taylor & Francis
Introduction: Kawasaki disease (KD) is a form of systemic vasculitis that can lead to
complications of coronary artery lesions (CAL). Diagnosis without delay and treatment with …