When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging
An epidemic of obesity has affected large portions of the world, increasing the risk of
developing many different age-associated diseases, including cancer, cardiovascular …
developing many different age-associated diseases, including cancer, cardiovascular …
Protein appetite as an integrator in the obesity system: the protein leverage hypothesis
D Raubenheimer, SJ Simpson - … Transactions of the …, 2023 - royalsocietypublishing.org
Despite the large volume and extensive range of obesity research, there is substantial
disagreement on the causes and effective preventative strategies. We suggest the field will …
disagreement on the causes and effective preventative strategies. We suggest the field will …
[HTML][HTML] Gut bacterial nutrient preferences quantified in vivo
Great progress has been made in understanding gut microbiomes' products and their effects
on health and disease. Less attention, however, has been given to the inputs that gut …
on health and disease. Less attention, however, has been given to the inputs that gut …
[HTML][HTML] Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
Low-protein diets promote metabolic health in humans and rodents. Despite evidence that
sex and genetic background are key factors in the response to diet, most protein intake …
sex and genetic background are key factors in the response to diet, most protein intake …
[HTML][HTML] Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer
solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial …
solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial …
Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice
Low-protein diets promote health and longevity in diverse species. Restriction of the
branched-chain amino acids (BCAAs) leucine, isoleucine, and valine recapitulates many of …
branched-chain amino acids (BCAAs) leucine, isoleucine, and valine recapitulates many of …
[HTML][HTML] Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma
S Talamantes, M Lisjak, EH Gilglioni… - JHEP Reports, 2023 - Elsevier
Obesity-related complications such as non-alcoholic fatty liver disease (NAFLD) and type 2
diabetes (T2D) are well-established risk factors for the development of hepatocellular …
diabetes (T2D) are well-established risk factors for the development of hepatocellular …
Amino acid transporters as modulators of glucose homeostasis
S Bröer - Trends in Endocrinology & Metabolism, 2022 - cell.com
Amino acids modulate glucose homeostasis. Cytosolic levels of amino acids are regulated
by amino acid transporters, modulating insulin release, protein synthesis, cell proliferation …
by amino acid transporters, modulating insulin release, protein synthesis, cell proliferation …
Relationship between carbohydrate intake (quantity, quality, and time eaten) and mortality (total, cardiovascular, and diabetes): assessment of 2003–2014 national …
W Hou, T Han, X Sun, Y Chen, J Xu, Y Wang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE In this study we investigated the association of the quantity, quality, and timing
of carbohydrate intake with all-cause, cardiovascular disease (CVD), and diabetes mortality …
of carbohydrate intake with all-cause, cardiovascular disease (CVD), and diabetes mortality …
[HTML][HTML] Whole-grain intake in the Mediterranean diet and a low protein to carbohydrates ratio can help to reduce mortality from cardiovascular disease, slow down the …
C Capurso - Nutrients, 2021 - mdpi.com
Increase in the aging population is a phenomenon all over the world. Maintaining good
functional ability, good mental health, and cognitive function in the absence of severe …
functional ability, good mental health, and cognitive function in the absence of severe …