The Versatile Mutational Resistome of Pseudomonas aeruginosa

C López-Causapé, G Cabot… - Frontiers in …, 2018 - frontiersin.org
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …

CRISPR/Cas9‐Based Counterselection Boosts Recombineering Efficiency in Pseudomonas putida

T Aparicio, V de Lorenzo… - Biotechnology …, 2018 - Wiley Online Library
While adoption of single‐stranded DNA recombineering techniques has greatly eased
genetic design of the platform strain Pseudomonas putida KT2440, available methods still …

Widely used benzalkonium chloride disinfectants can promote antibiotic resistance

M Kim, MR Weigand, S Oh, JK Hatt… - Applied and …, 2018 - Am Soc Microbiol
While the misuse of antibiotics has clearly contributed to the emergence and proliferation of
resistant bacterial pathogens, with major health consequences, it remains less clear if the …

Improved bacterial recombineering by parallelized protein discovery

TM Wannier, A Nyerges… - Proceedings of the …, 2020 - National Acad Sciences
Exploiting bacteriophage-derived homologous recombination processes has enabled
precise, multiplex editing of microbial genomes and the construction of billions of …

Development of giant bacteriophage ϕKZ is independent of the host transcription apparatus

PJ Ceyssens, L Minakhin, A Van den Bossche… - Journal of …, 2014 - Am Soc Microbiol
Pseudomonas aeruginosa bacteriophage ϕKZ is the type representative of the giant phage
genus, which is characterized by unusually large virions and genomes. By unraveling the …

Exposure to Mutagenic Disinfection Byproducts Leads to Increase of Antibiotic Resistance in Pseudomonas aeruginosa

L Lv, T Jiang, S Zhang, X Yu - Environmental science & …, 2014 - ACS Publications
Bacterial antibiotic resistance (BAR) in drinking water has become a global issue because of
its risks on the public health. Usually, the antibiotic concentrations in drinking water are too …

Interspecies competition triggers virulence and mutability in Candida albicansPseudomonas aeruginosa mixed biofilms

A Trejo-Hernández, A Andrade-Domínguez… - The ISME …, 2014 - academic.oup.com
Inter-kingdom and interspecies interactions are ubiquitous in nature and are important for
the survival of species and ecological balance. The investigation of microbe-microbe …

Reconciliation of genome-scale metabolic reconstructions for comparative systems analysis

MA Oberhardt, J Puchałka… - PLoS computational …, 2011 - journals.plos.org
In the past decade, over 50 genome-scale metabolic reconstructions have been built for a
variety of single-and multi-cellular organisms. These reconstructions have enabled a host of …

The metabolic redox regime of Pseudomonas putida tunes its evolvability toward novel xenobiotic substrates

Ö Akkaya, DR Pérez-Pantoja, B Calles, PI Nikel… - MBio, 2018 - Am Soc Microbiol
During evolution of biodegradation pathways for xenobiotic compounds involving Rieske
nonheme iron oxygenases, the transition toward novel substrates is frequently associated …

The Ssr protein (T1E_1405) from Pseudomonas putida DOT‐T1E enables oligonucleotide‐based recombineering in platform strain P. putida EM42

T Aparicio, SI Jensen, AT Nielsen… - Biotechnology …, 2016 - Wiley Online Library
Some strains of the soil bacterium Pseudomonas putida have become in recent years
platforms of choice for hosting biotransformations of industrial interest. Despite availability of …