Burkholderia is a genus within the β-Proteobacteriaceae that contains at least 90 validly
named species which can be found in a diverse range of environments. A number of …

Background Chronic infection with Burkholderia cepacia complex species remains a
significant problem for clinicians treating people with cystic fibrosis. Colonisation with …

Clostridioides difficile infection (CDI) remains an urgent global One Health threat. The
genetic heterogeneity seen across C. difficile underscores its wide ecological versatility and …

The Pseudomonas genus includes many species living in diverse environments and hosts. It
is important to understand which are the major evolutionary groups and what are the …

Due to the increase in multidrug-resistant microorganisms, the investigation of novel or more
efficient antimicrobial compounds is essential. The World Health Organization issued a list of …

Polyketide synthases assemble diverse natural products with numerous important
applications. The thioester intermediates in polyketide assembly are covalently tethered to …

The qualified presumption of safety (QPS) procedure was developed to provide a
harmonised generic pre‐evaluation to support safety risk assessments of biological agents …

Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among
bacteria, yet, despite extensive studies in the last decade, their biological importance …

Background The erratic alterations in climate being experienced in agriculture, such as
extended periods of drought or heavy rainfalls, are bringing increasing concerns about …

The bulgecins are iminosaccharide secondary metabolites of the Gram-negative bacterium
Paraburkholderia acidophila and inhibitors of lytic transglycosylases of bacterial cell-wall …