Many Gram-negative bacteria use the sophisticated type II secretion system (T2SS) to
translocate a wide range of proteins from the periplasm across the outer membrane. The …

Homologues of the protein constituents of the Klebsiella pneumoniae (Klebsiella oxytoca)
type II secreton (T2S), the Pseudomonas aeruginosa type IV pilus/fimbrium biogenesis …

The genome of the opportunistic pathogen Pseudomonas aeruginosa encodes over 60 two-
component sensor kinases and uses several (including RetS and GacS) to reciprocally …

Protein secretion systems are molecular nanomachines used by Gram-negative bacteria to
thrive within their environment. They are used to release enzymes that hydrolyze complex …

The type II secretion pathway or the main terminal branch of the general secretion pathway,
as it has also been referred to, is widely distributed among Proteobacteria, in which it is …

The cell envelope of Gram-negative bacteria is composed of two membranes, which are
separated by the peptidoglycan-containing periplasm. Whereas the envelope forms an …

abstract Gram-negative bacteria use the type II secretion system to transport a large number
of secreted proteins from the periplasmic space into the extracellular environment. Many of …

Protein trafficking across the bacterial envelope is a process that contributes to the
organisation and integrity of the cell. It is the foundation for establishing contact and …

The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …

Gram-negative bacteria have evolved several secretory pathways to release enzymes or
toxins into the surrounding environment or into the target cells. The type II secretion system …