Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities

X Jiang, K Wu, R Bai, P Zhang, Y Zhang - European Journal of Medicinal …, 2022 - Elsevier
Quinoxalinones are a class of heterocyclic compounds which attract extensive attention
owing to their potential in the field of organic synthesis and medicinal chemistry. During the …

A review on multipurpose potential of bioactive heterocycle quinoxaline

G Chawla, O Gupta, T Pradhan - ChemistrySelect, 2023 - Wiley Online Library
In last few decades, nitrogen‐containing heterocycles have maintained their status as an
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …

Design and synthesis of novel 1, 2, 3-triazole linked hybrids: Molecular docking, MD simulation, and their antidiabetic efficacy as α-Amylase inhibitors

AR Zala, HN Naik, I Ahmad, H Patel, S Jauhari… - Journal of Molecular …, 2023 - Elsevier
Abstract Novel 1, 2, 3-triazole linked coumarin and cinnamic acid analogs were designed,
synthesized, characterized, and evaluated for their ability to inhibit the α-amylase enzyme in …

Novel antioxidant quinoxaline derivative: Synthesis, crystal structure, theoretical studies, antidiabetic activity and molecular docking study

M Missioui, S Mortada, W Guerrab, G Serdaroğlu… - Journal of Molecular …, 2021 - Elsevier
Abstract New quinoxaline derivative, N-(4-methyl-2-nitrophenyl)-2-(3-methyl-2-
oxoquinoxalin-1 (2H)-yl) acetamide (NPOQA) has been synthesized and characterized by …

Docking of disordered independent molecules of novel crystal structure of (N-(4-methoxyphenyl)-2-(3-methyl-2-oxo-3, 4-dihydroquinoxalin-1 (2H)-yl) acetamide as …

M Missioui, MA Said, G Demirtaş, JT Mague… - Journal of Molecular …, 2022 - Elsevier
Abstract New quinoxaline derivative, N-(4-methyl-2-nitrophenyl)-2-(3-methyl-2-
oxoquinoxalin-1 (2H)-yl) acetamide (NMPOQA= disordered molecules NMPOQAa (50.3 …

Molecular engineering of D-π-A-type structures based on nitrobenzofurazan (NBD) derivatives for both organic solar cells and nonlinear optical response

B Abdelaziz, Z Mazouz, B Gassoumi… - Journal of Molecular …, 2024 - Elsevier
The electronic, photo-physical, and nonlinear optical (NLO) properties of small molecules
from nitrobenzofurazan (NBD) derivatives have been fine-tuned through the introduction of …

Jahn-Teller distortion in SP-like [Cu (bipy)(triamine)]. 2BF4 complexes with novel NH… F/CH… F synthon: XRD/HSA-interactions, physicochemical, electrochemical …

A AlAli, M Al-Noaimi, A AlObaid, HA Khamees… - Journal of Molecular …, 2023 - Elsevier
Abstract New [Cu (bipy)(NNN)]. 2BF 4 water soluble dicationic complexes were made
available starting from [Cu (bipy) 2 Br] Br. The two complexes were isolated in excellent yield …

A possible potential COVID-19 drug candidate: Diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1 (2H)-yl) acetyl) hydrazono) malonate: Docking of disordered independent …

M Missioui, MA Said, G Demirtaş, JT Mague… - Arabian Journal of …, 2022 - Elsevier
This study reports the synthesis, characterization and importance of a novel diethyl 2-(2-(2-
(3-methyl-2-oxoquinoxalin-1 (2H)-yl) acetyl) hydrazono) malonate (MQOAHM). Two …

Computational studies on optoelectronic and nonlinear optical properties of para-substituted nitrobenzofurazan compound

I Chérif, H Raissi, K Abiedh, B Gassoumi… - Materials Today …, 2023 - Elsevier
The activated chlorine atom on 4-chloro-7-nitrobenzofurazan (NBD-chloride, NBD-Cl) by
piperidine, secondary amine, yields a product of the nucleophilic aromatic substitution (SN …

[HTML][HTML] Greener pastures in evaluating antidiabetic drug for a quinoxaline Derivative: Synthesis, Characterization, Molecular Docking, in vitro and HSA/DFT/XRD …

M Missioui, S Mortada, W Guerrab, G Demirtaş… - Arabian Journal of …, 2022 - Elsevier
In an effort to develop a potent antidiabetic drug, new quinoxaline derivative, 2-(4-((3-methyl-
2-oxoquinoxalin-1 (2H)-yl) methyl)-4, 5-dihydro-1H-1, 2, 3-triazol-1-yl)-N-(p-tolyl) acetamide …