Genome clashes in hybrids: insights from gene expression
In interspecific hybrids, novel phenotypes often emerge from the interaction of two divergent
genomes. Interactions between the two transcriptional networks are assumed to contribute …
genomes. Interactions between the two transcriptional networks are assumed to contribute …
Compensatory cis-trans Evolution and the Dysregulation of Gene Expression in Interspecific Hybrids of Drosophila
Hybrids between species are often characterized by novel gene-expression patterns. A
recent study on allele-specific gene expression in hybrids between species of Drosophila …
recent study on allele-specific gene expression in hybrids between species of Drosophila …
Is phage display technology on target for developing peptide-based cancer drugs?
LA Landon, J Zou, SL Deutscher - Current drug discovery …, 2004 - ingentaconnect.com
New tumor targeting agents are required to advance cancer diagnosis and treatment.
Bacteriophage (phage) display technology, a molecular genetic means of combinatorial …
Bacteriophage (phage) display technology, a molecular genetic means of combinatorial …
Protein–protein and protein–DNA interactions of σ70 region 4 involved in transcription activation by λcI
The cI protein of bacteriophage λ (λcI) activates transcription from promoter PRM through an
acidic patch on the surface of its DNA-binding domain. Genetic evidence suggests that this …
acidic patch on the surface of its DNA-binding domain. Genetic evidence suggests that this …
Functional conservation of Rel binding sites in drosophilid genomes
RR Copley, M Totrov, J Linnell, S Field… - Genome …, 2007 - genome.cshlp.org
Evolutionary constraints on gene regulatory elements are poorly understood: Little is known
about how the strength of transcription factor binding correlates with DNA sequence …
about how the strength of transcription factor binding correlates with DNA sequence …
Sensitive genome-wide screen for low secondary enzymatic activities: the YjbQ family shows thiamin phosphate synthase activity
E Morett, G Saab-Rincón, L Olvera, M Olvera… - Journal of molecular …, 2008 - Elsevier
Contemporary enzymes are highly efficient and selective catalysts. However, due to the
intrinsically very reactive nature of active sites, gratuitous secondary reactions are practically …
intrinsically very reactive nature of active sites, gratuitous secondary reactions are practically …
Secondary structure and DNA binding by the C‐terminal domain of the transcriptional activator NifA from Klebsiella pneumoniae
P Ray, KJ Smith, RA Parslow, R Dixon… - Nucleic acids …, 2002 - academic.oup.com
Abstract The NifA protein of Klebsiella pneumoniae is required for transcriptional activation
of all nitrogen fixation (nif) operons except the regulatory nifLA genes. At these operons, NifA …
of all nitrogen fixation (nif) operons except the regulatory nifLA genes. At these operons, NifA …
[PDF][PDF] Secondary structure and DNA binding by the C-terminal domain of the transcriptional activator
P Ray, KJ Smith, RA Parslow, R Dixon, EI Hyde - Citeseer
ABSTRACT The NifA protein of Klebsiella pneumoniae is required for transcriptional
activation of all nitrogen fixation (nif) operons except the regulatory nifLA genes. At these …
activation of all nitrogen fixation (nif) operons except the regulatory nifLA genes. At these …