An evolving new paradigm: endothelial cells–conditional innate immune cells
Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …
processes. ECs also actively participate in both innate and adaptive immune responses …
[HTML][HTML] Nanobody: the “magic bullet” for molecular imaging?
Molecular imaging involves the non-invasive investigation of biological processes in vivo at
the cellular and molecular level, which can play diverse roles in better understanding and …
the cellular and molecular level, which can play diverse roles in better understanding and …
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
W Jiang, WJ Swiggard, C Heufler, M Peng, A Mirza… - Nature, 1995 - nature.com
DENDRITIC cells and thymic epithelial cells perform important immunoregulatory functions
by presenting antigens in the form of peptides bound to cell-surface major histocompatibility …
by presenting antigens in the form of peptides bound to cell-surface major histocompatibility …
The mannose receptor family
L East, CM Isacke - Biochimica et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
The mannose receptor family comprises four glycoproteins each of which is a type I
transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II …
transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II …
The mannose receptor is a pattern recognition receptor involved in host defense
PD Stahl, RAB Ezekowitz - Current opinion in immunology, 1998 - Elsevier
The mannose receptor recognizes the patterns of carbohydrates that decorate the surfaces
and cell walls of infectious agents. This macrophage and dendritic cell pattern-recognition …
and cell walls of infectious agents. This macrophage and dendritic cell pattern-recognition …
Synthetic macromolecules as therapeutics that overcome resistance in cancer and microbial infection
Synthetic macromolecular antimicrobials have shown efficacy in the treatment of multidrug
resistant (MDR) pathogens. These synthetic macromolecules, inspired by Nature's …
resistant (MDR) pathogens. These synthetic macromolecules, inspired by Nature's …
[HTML][HTML] C-type lectins and phagocytosis
AM Kerrigan, GD Brown - Immunobiology, 2009 - Elsevier
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors
(PRRs) bind to conserved microbial structures and activate host defence systems, including …
(PRRs) bind to conserved microbial structures and activate host defence systems, including …
Animal lectins
HJ Gabius - European journal of biochemistry, 1997 - Wiley Online Library
Protein and lipid glycosylation is no longer considered as a topic whose appeal is restricted
to a limited number of analytical experts perseveringly pursuing the comprehensive …
to a limited number of analytical experts perseveringly pursuing the comprehensive …
The mannose receptor: linking homeostasis and immunity through sugar recognition
PR Taylor, S Gordon, L Martinez-Pomares - Trends in immunology, 2005 - cell.com
The mannose receptor (MR) can potentially internalize compounds that are recognized by
three binding sites located in its extracellular region. It is subject to proteolytic processing …
three binding sites located in its extracellular region. It is subject to proteolytic processing …
Immune dysfunction and bacterial coinfections following influenza
DW Metzger, K Sun - The Journal of Immunology, 2013 - journals.aai.org
Secondary pulmonary infections by encapsulated bacteria including Streptococcus
pneumoniae and Staphylococcus aureus following influenza represent a common and …
pneumoniae and Staphylococcus aureus following influenza represent a common and …