Neuroendocrine prostate cancer: subtypes, biology, and clinical outcomes

R Aggarwal, T Zhang, EJ Small… - Journal of the National …, 2014 - jnccn.org
Neuroendocrine prostate cancer (NEPC) encompasses various clinical contexts, ranging
from the de novo presentation of small cell prostatic carcinoma to a treatment-emergent …

Use of modern imaging methods to facilitate trials of metastasis-directed therapy for oligometastatic disease in prostate cancer: a consensus recommendation from the …

FE Lecouvet, DE Oprea-Lager, Y Liu, P Ost… - The Lancet …, 2018 - thelancet.com
Oligometastatic disease represents a clinical and anatomical manifestation between
localised and polymetastatic disease. In prostate cancer, as with other cancers, recognition …

Randomized phase III noninferiority study comparing two radiotherapy fractionation schedules in patients with low-risk prostate cancer

WR Lee, JJ Dignam, MB Amin, DW Bruner… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Conventional radiotherapy (C-RT) treatment schedules for patients with prostate
cancer typically require 40 to 45 treatments that take place from> 8 to 9 weeks. Preclinical …

Comparison of bone scintigraphy and 68Ga-PSMA PET for skeletal staging in prostate cancer

T Pyka, S Okamoto, M Dahlbender, R Tauber… - European journal of …, 2016 - Springer
Purpose The aim of our study was to compare the diagnostic performance of 68 Ga-PSMA
PET and 99m Tc bone scintigraphy (BS) for the detection of bone metastases in prostate …

Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a …

K Fizazi, L Faivre, F Lesaunier, R Delva… - The Lancet …, 2015 - thelancet.com
Background Early risk-stratified chemotherapy is a standard treatment for breast, colorectal,
and lung cancers, but not for high-risk localised prostate cancer. Combined docetaxel and …

Trends in treatment patterns and outcomes for ductal carcinoma in situ

M Worni, I Akushevich, R Greenup… - Journal of the …, 2015 - academic.oup.com
Background: Impact of contemporary treatment of pre-invasive breast cancer (ductal
carcinoma in situ [DCIS]) on long-term outcomes remains poorly defined. We aimed to …

Long-term results of active surveillance in the Göteborg randomized, population-based prostate cancer screening trial

RA Godtman, E Holmberg, A Khatami, CG Pihl… - European urology, 2016 - Elsevier
Background Active surveillance (AS) has become a well-accepted and widely used
treatment strategy. Objective To assess the long-term safety of AS for men with screen …

Comparison of hybrid 68Ga-PSMA PET/MRI and 68Ga-PSMA PET/CT in the evaluation of lymph node and bone metastases of prostate cancer

MT Freitag, JP Radtke, BA Hadaschik… - European journal of …, 2016 - Springer
Purpose To evaluate the reproducibility of the combination of hybrid PET/MRI and the 68 Ga-
PSMA-11 tracer in depicting lymph node (LN) and bone metastases of prostate cancer (PC) …

Inhibitors of the PI3K/Akt/mTOR pathway in prostate cancer chemoprevention and intervention

NM Roudsari, NA Lashgari, S Momtaz, S Abaft… - Pharmaceutics, 2021 - mdpi.com
The phosphatidylinositol 3-kinase (PI3K)/serine-threonine kinase (Akt)/mammalian target of
the rapamycin (mTOR)-signaling pathway has been suggested to have connections with the …

Development of standardized image interpretation for 68Ga-PSMA PET/CT to detect prostate cancer recurrent lesions

S Fanti, S Minozzi, JJ Morigi, F Giesel, F Ceci… - European journal of …, 2017 - Springer
Methods After primary treatment, biochemical relapse (BCR) occurs in a substantial number
of patients with prostate cancer (PCa). PET/CT imaging with prostate-specific membrane …