Simple Summary Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)
plays an important role in apoptosis and tumor immunosurveillance. Because TRAIL …

The year 2004 represents a milestone for the biosensor research community: in this year,
over 1000 articles were published describing experiments performed using commercially …

How the thermodynamic stability effects of protein mutations (ΔΔG) are distributed is a
fundamental property related to the architecture, tolerance to mutations (mutational …

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential anticancer
drug that selectively induces apoptosis in a variety of cancer cells by interacting with death …

Transcriptional coactivators p300 and CBP catalyze the acetylation of lysine residues in
histone proteins. Upregulation of p300 and CBP has been associated with lung, colorectal …

The key to making a practicable hydrogel for pharmaceutical or medical purposes is to
endow it with relevant properties, ie, facile fabrication, gelation time-controllability, and in …

Background Apoptosis can be executed through a mitochondria-dependent (intrinsic) and a
death receptor–dependent, mitochondria-independent (extrinsic) pathway. The intrinsic …

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential anticancer
agent that selectively induces apoptosis in a variety of cancer cells by interacting with death …

Receptor tyrosine kinases, such as VEGFR, PDGFR and EGFR, play important roles in renal
cancer. In this study, we investigated EGFR knockout as a therapeutic approach in renal cell …

Bacillus pumilus SG2, a halotolerant strain, expresses two major chitinases designated ChiS
and ChiL that were induced by chitin and secreted into the supernatant. The present work …