Neurotrophic keratopathy: current challenges and future prospects

E NaPier, M Camacho, TF McDevitt… - Annals of …, 2022 - Taylor & Francis
Neurotrophic keratopathy (NK), or neurotrophic keratitis, is a degenerative condition that
results from decreased innervation to the cornea. The cornea is innervated by the …

PRP in wound healing applications

P Oneto, J Etulain - Platelets, 2021 - Taylor & Francis
Platelets play a crucial role in hemostasis, tissue regeneration and host defense. Based on
these settings, platelet-rich plasma (PRP) and its derivatives are therapeutically used to …

Progress in the use of plasma rich in growth factors in ophthalmology: From ocular surface to ocular fundus

E Anitua, B De la Sen-Corcuera, G Orive… - Expert opinion on …, 2022 - Taylor & Francis
Introduction The use of blood derivatives and especially Plasma rich in growth factors
(PRGF), for regenerative purposes has been a common trend along the last decades in the …

[HTML][HTML] Future directions in managing aniridia-associated keratopathy

AJH Van Velthoven, TP Utheim, M Notara… - Survey of …, 2023 - Elsevier
Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia
and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal …

[HTML][HTML] Umbilical cord blood and serum for the treatment of ocular diseases: a comprehensive review

G Giannaccare, A Carnevali, C Senni… - Ophthalmology and …, 2020 - Springer
Several blood derivatives have been proposed for the treatment of various ocular diseases
that affect either the anterior or the posterior segment of the eye. Blood sources may range …

[HTML][HTML] Achieving net-zero in the dry eye disease care pathway

SG Latham, RL Williams, LM Grover, S Rauz - Eye, 2024 - nature.com
Climate change is a threat to human health and wellbeing across the world. In recent years,
there has been a surge in awareness of this crisis, leading to many countries and …

[HTML][HTML] Tear film interferometry assessment after intense pulsed light in dry eye disease: A randomized, single masked, sham-controlled study

Y Song, S Yu, X He, L Yang, Y Wu, G Qin… - Contact Lens and …, 2022 - Elsevier
Abstract Background Inadequate meibomian glands (MGs) secretion can lead to dry eye
signs and symptoms. Tear film lipid layer (TFLL) secreted by MGs protects and prevents …

Human platelets and derived products in treating ocular surface diseases–a systematic review

J You, C Hodge, M Hoque, C Petsoglou… - Clinical …, 2020 - Taylor & Francis
Human platelet products have emerged as an alternative treatment for a range of ocular
surface diseases such as dry eye and corneal ulceration. With significant therapeutic …

[HTML][HTML] New perspectives in the pathophysiology and treatment of pain in patients with dry eye disease

G Giannaccare, C Ghelardini, A Mancini… - Journal of Clinical …, 2021 - mdpi.com
Ocular discomfort and eye pain are frequently reported by patients with dry eye disease
(DED), and their management remains a real therapeutic challenge for the Ophthalmologist …

Eye drops of human origin—Current status and future needs: Report on the workshop organized by the ISBT Working Party for Cellular Therapies

C Gabriel, DC Marks, R Henschler… - Vox …, 2023 - Wiley Online Library
Abstract Background and Objectives Serum eye drops (SEDs) are used to treat ocular
surface disease (OSD) and to promote ocular surface renewal. However, their use and …